AOC2

Gene Symbol	AOC2
Entrez Gene	314
Alt Symbol	DAO2, RAO
Species	Human
Gene Type	protein-coding
Description	amine oxidase, copper containing 2 (retina-specific)
Other Description	SSAO|retina-specific copper amine oxidase|semicarbazide-sensitive amine oxidase
Swissprots	O75105 O75106 Q9UNY0 Q4TTW5 O00120 A5PKW2
Accessions	AAY43129 BAA32589 BAA32590 EAW60895 EAW60896 O75106 AF081363 AAD39345 BC142641 AAI42642 CA425343 CN355968 D88213 BAA19001 DQ426861 ABD90530 NM_001158 NP_001149 NM_009590 NP_033720
Function	Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina. {ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076}.
Subcellular Location	Isoform 1: Cell membrane; Peripheral membrane protein. Note=Present on the surface of the cells.
Tissue Specificity	Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis. {ECO:0000269|PubMed:12755418, ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076}.
Top Pathways	Glycine, serine and threonine metabolism, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RAO CRISPR/Cas9 KO Plasmid (h) - sc-410686 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO HDR Plasmid (h) - sc-410686-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO Double Nickase Plasmid (h) - sc-410686-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO Double Nickase Plasmid (h2) - sc-410686-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO CRISPR Activation Plasmid (h) - sc-410686-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO CRISPR Activation Plasmid (h2) - sc-410686-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO Lentiviral Activation Particles (h) - sc-410686-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO Lentiviral Activation Particles (h2) - sc-410686-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

RAO siRNA (h) - sc-40898 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RAO shRNA Plasmid (h) - sc-40898-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

RAO shRNA (h) Lentiviral Particles - sc-40898-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AOC2 RNAi - H00000314-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

AOC2 RNAi - H00000314-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU013101 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3274 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3274 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03021 from Sigma-Aldrich Category miRNA

AOC2 siRNA (Human) - CRH0216 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

AOC2 - MBS8210862 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human AOC2 (NM_001158.3) - SHH237658 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human AOC2(NM_001158.3) - SHG062451 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human AOC2(NM_009590.2) - SHG062533 from Creative biogene Category siRNA Species Reactivities Human

Human AOC2 siRNA - orb260718 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

AOC2 shRNA Plasmid (Human) - CHH0216 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

AOC2 miRNA 3'UTR clone - MiUTR1H-00429 from Creative biogene Species Reactivities Human

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