Gene Symbol | AOC2 |
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Entrez Gene | 314 |
Alt Symbol | DAO2, RAO |
Species | Human |
Gene Type | protein-coding |
Description | amine oxidase, copper containing 2 (retina-specific) |
Other Description | SSAO|retina-specific copper amine oxidase|semicarbazide-sensitive amine oxidase |
Swissprots | O75105 O75106 Q9UNY0 Q4TTW5 O00120 A5PKW2 |
Accessions | AAY43129 BAA32589 BAA32590 EAW60895 EAW60896 O75106 AF081363 AAD39345 BC142641 AAI42642 CA425343 CN355968 D88213 BAA19001 DQ426861 ABD90530 NM_001158 NP_001149 NM_009590 NP_033720 |
Function | Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina. {ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076}. |
Subcellular Location | Isoform 1: Cell membrane; Peripheral membrane protein. Note=Present on the surface of the cells. |
Tissue Specificity | Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis. {ECO:0000269|PubMed:12755418, ECO:0000269|PubMed:17400359, ECO:0000269|PubMed:19588076}. |
Top Pathways | Glycine, serine and threonine metabolism, Phenylalanine metabolism, Tyrosine metabolism, beta-Alanine metabolism |
RAO (T-16) - sc-21932 from Santa Cruz Biotechnology
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RAO (F-17) - sc-21929 from Santa Cruz Biotechnology
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Anti-AOC2 antibody - ab83734 from Abcam
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Anti-AOC2 antibody - ab72780 from Abcam
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Anti-AOC2 antibody - ab171801 from Abcam
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Anti-AOC2 antibody - ab183762 from Abcam
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Anti-AOC2 / SSAO Antibody - LS-C309463 from LifeSpan Bioscience
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Anti-AOC2 / SSAO Antibody (aa684-733) - LS-C102156 from LifeSpan Bioscience
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Anti-AOC2 / SSAO Antibody (aa401-450) - LS-C80691 from LifeSpan Bioscience
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AOC2 Antibody - NBP1-62442 from Novus Biologicals
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AOC2 Antibody - NBP1-62443 from Novus Biologicals
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AOC2 Antibody - NBP2-33849 from Novus Biologicals
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AOC2 Antibody - H00000314-A01 from Novus Biologicals
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AOC2 Antibody - H00000314-B01 from Novus Biologicals
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AOC2 Antibody - H00000314-B01P from Novus Biologicals
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AOC2 Antibody - H00000314-D01P from Novus Biologicals
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Anti-AOC2 antibody produced in rabbit - HPA057779 from Sigma-Aldrich
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Anti-AOC2 antibody produced in rabbit - SAB2100128 from Sigma-Aldrich
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Anti-AOC2 antibody produced in rabbit - AV45055 from Sigma-Aldrich
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Anti-AOC2 (171-185) antibody produced in rabbit - A3235 from Sigma-Aldrich
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AOC2 antibody - middle region (ARP45055_P050) - ARP45055_P050 from Aviva Systems Biology
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AOC2 antibody - middle region (ARP45057_P050) - ARP45057_P050 from Aviva Systems Biology
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AOC2 antibody - GTX112397 from GeneTex
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AOC2 antibody, Internal - GTX46578 from GeneTex
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AOC2 antibody, Internal - GTX46579 from GeneTex
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