Gene Symbol | STX1A |
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Entrez Gene | 6804 |
Alt Symbol | HPC-1, P35-1, STX1, SYN1A |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin 1A (brain) |
Other Description | neuron-specific antigen HPC-1|syntaxin-1A |
Swissprots | O15447 Q16623 Q12936 Q9BPZ6 Q75MD9 Q7Z5K3 O15448 |
Accessions | AAB65500 AAK54507 AAS07469 AAS07470 EAW69649 EAW69650 EAW69651 EAW69652 EAW69653 EAW69654 EAW69655 Q16623 AB086954 BAC78519 AI951874 AK299959 BAG61785 AK313980 BAG36694 BC000444 BC003011 AAH03011 BC064644 AAH64644 CR457018 CAG33299 D37932 BAA07151 DA159446 GQ129291 ACT64425 GQ129292 ACT64426 KJ534952 AHW56592 KJ534980 AHW56620 L37792 AAA53519 U12918 AAA20940 XM_011516541 XP_011514843 XR_242263 XR_927527 XR_927528 NM_001165903 NP_001159375 NM_004603 NP_004594 |
Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. |
Tissue Specificity | Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. {ECO:0000269|PubMed:10644452}. |
Top Pathways | Synaptic vesicle cycle, Amphetamine addiction, SNARE interactions in vesicular transport |
Syntaxin 1A Antibody - 13002 from Cell Signaling Technology
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Syntaxin (C-19) - sc-7562 from Santa Cruz Biotechnology
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Syntaxin 1 (C-5) - sc-17836 from Santa Cruz Biotechnology
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Syntaxin 1 (HPC-1) - sc-12736 from Santa Cruz Biotechnology
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Anti-Syntaxin 1a (phospho S14) antibody - ab63571 from Abcam
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Anti-Syntaxin 1a (phospho S14) antibody - ab182643 from Abcam
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Anti-Syntaxin 1a (phospho S14) antibody - ab195830 from Abcam
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Anti-Syntaxin 1a antibody - ab118359 from Abcam
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Anti-Syntaxin 1a antibody - ab103179 from Abcam
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Anti-Syntaxin 1a antibody - ab167617 from Abcam
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Anti-Syntaxin 1a antibody - ab74535 from Abcam
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Anti-Syntaxin 1a antibody [EPR11072(B)] - ab170890 from Abcam
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Anti-Syntaxin 1a antibody [EPR11073(B)] - ab170889 from Abcam
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Anti-Syntaxin 1a antibody [SP36] - ab73913 from Abcam
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Anti-Syntaxin 1a antibody [SP36], prediluted - ab73915 from Abcam
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Anti-STX1A / Syntaxin 1A Antibody - LS-C39414 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody - LS-C63315 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody - LS-C89914 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody (aa1-251) - LS-C132344 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody (aa36-65, AP) - LS-C270619 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody (aa36-65, APC) - LS-C270620 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody (aa32-81) - LS-C146527 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody (N-Terminus) - LS-C112324 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody (clone HPC-1) - LS-C179639 from LifeSpan Bioscience
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Anti-STX1A / Syntaxin 1A Antibody - LS-C152929 from LifeSpan Bioscience
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