Gene Symbol | STX1A |
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Entrez Gene | 6804 |
Alt Symbol | HPC-1, P35-1, STX1, SYN1A |
Species | Human |
Gene Type | protein-coding |
Description | syntaxin 1A (brain) |
Other Description | neuron-specific antigen HPC-1|syntaxin-1A |
Swissprots | O15447 Q16623 Q12936 Q9BPZ6 Q75MD9 Q7Z5K3 O15448 |
Accessions | AAB65500 AAK54507 AAS07469 AAS07470 EAW69649 EAW69650 EAW69651 EAW69652 EAW69653 EAW69654 EAW69655 Q16623 AB086954 BAC78519 AI951874 AK299959 BAG61785 AK313980 BAG36694 BC000444 BC003011 AAH03011 BC064644 AAH64644 CR457018 CAG33299 D37932 BAA07151 DA159446 GQ129291 ACT64425 GQ129292 ACT64426 KJ534952 AHW56592 KJ534980 AHW56620 L37792 AAA53519 U12918 AAA20940 XM_011516541 XP_011514843 XR_242263 XR_927527 XR_927528 NM_001165903 NP_001159375 NM_004603 NP_004594 |
Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. |
Tissue Specificity | Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain. {ECO:0000269|PubMed:10644452}. |
Top Pathways | Synaptic vesicle cycle, Amphetamine addiction, SNARE interactions in vesicular transport |
Human Syntaxin 1a full length protein - ab132963 from Abcam
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Human Syntaxin 1a protein fragment - ab86442 from Abcam
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Human Syntaxin 1a protein fragment - ab73827 from Abcam
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Rat Syntaxin 1a peptide - ab41451 from Abcam
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Rat Syntaxin 1a peptide - ab41452 from Abcam
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STX1A / Syntaxin 1A Antibody Blocking Peptide - LS-E10721 from LifeSpan Bioscience
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STX1A / Syntaxin 1A Antibody Blocking Peptide - LS-E21764 from LifeSpan Bioscience
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STX1A / Syntaxin 1A Antibody Blocking Peptide - LS-E10333 from LifeSpan Bioscience
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STX1A / Syntaxin 1A Antibody Blocking Peptide - LS-E29702 from LifeSpan Bioscience
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STX1A / Syntaxin 1A Antibody Blocking Peptide - LS-E29703 from LifeSpan Bioscience
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STX1A / STX1B Antibody Blocking Peptide - LS-E25927 from LifeSpan Bioscience
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Syntaxin 1A Recombinant Protein - H00006804-P01 from Novus Biologicals
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Recombinant Human Syntaxin 1A Protein - NBC1-18338 from Novus Biologicals
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STX1A-Antibody-N-term-Blocking-Peptide - BP9813a from Abgent, a WuXi AppTec company
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STX1A/STX1B blocking peptide - GTX89481-PEP from GeneTex
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STX1A Protein (OPPA01448) - OPPA01448 from Aviva Systems Biology
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Human Syntaxin-1A protein - orb81398 from Biorbyt
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STX1A Blocking Peptide - 33R-4305 from Fitzgerald
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Syntaxin 1A protein - 30R-1094 from Fitzgerald
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Syntaxin 1A Peptide - AC21-0756-P from Abcore
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Syntaxin 1A / STX1A (1-226) - AR09086PU-L from Acris Antibodies
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Syntaxin 1A / STX1A (1-226) - AR09086PU-N from Acris Antibodies
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Syntaxin 1A / STX1A - H00006804-P01-10 from Acris Antibodies
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Syntaxin 1A / STX1A - H00006804-P01-25 from Acris Antibodies
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Syntaxin-1A, Human Recombinant - 228-11474-1 from RayBiotech
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