CATSPER4

Gene Symbol CATSPER4
Entrez Gene 378807
Alt Symbol -
Species Human
Gene Type protein-coding
Description cation channel, sperm associated 4
Other Description cation channel sperm-associated protein 4|ion channel CatSper4
Swissprots Q7RTX7 Q5VY71 A1A4W6
Accessions EAX07839 Q7RTX7 BC128138 AAI28139 BC128139 AAI28140 BC144663 BN000273 CAE30475 XM_011541432 XP_011539734 XM_011541433 XP_011539735 NM_198137 NP_937770
Function Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH. {ECO:0000269|PubMed:21412338, ECO:0000269|PubMed:21412339}.
Subcellular Location Cell projection, cilium, flagellum membrane; Multi-pass membrane protein. Note=Specifically located in the principal piece of sperm tail.
Tissue Specificity Testis-specific. {ECO:0000269|PubMed:12932298, ECO:0000269|PubMed:17347248}.

CatSper4 (T-17) - sc-83126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CATSPER4 antibody - C-terminal - ab197911 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling CATSPER4 with ab197911 at 1/50 dilution.

CATSPER4 Antibody - NBP1-46508 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Antibody - NBP1-91751 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: CATSPER4 Antibody [NBP1-91751] - Staining of human testis shows strong cytoplasmic positivity in spermatids.

CATSPER4 Polyclonal Antibody - bs-6422R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER4 antibody produced in rabbit - SAB4300988 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CATSPER4 antibody produced in rabbit - HPA045257 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CATSPER4: <B>Cat. No. HPA045257</B>: Immunohistochemical staining of human testis shows moderate cytoplasmic positivity in subset of cells in seminiferus ducts.

CATSPER4 Antibody - 36314 from Signalway Antibody

Prices $279.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36314 at dilution 1/50.

CATSPER4, Polyclonal Antibody - MBS2522758 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody - ESAP15128 from Elabscience

Prices $296.00, $485.00
Sizes 120 μl, 200 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of Human gastric cancer using CATSPER4 Polyclonal Antibody at dilution of 1:50

CATSPER4 Antibody - CSB-PA570108 from Cusabio

Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/50.

CATSPER4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-6422R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-6422R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-6422R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-6422R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, Cy3 Conjugated - bs-6422R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, Cy5 Conjugated - bs-6422R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, Cy5.5 Conjugated - bs-6422R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, Cy7 Conjugated - bs-6422R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, FITC Conjugated - bs-6422R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, Biotin Conjugated - bs-6422R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, HRP Conjugated - bs-6422R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4, Polyclonal Antibody - MBS9409347 from MyBioSource

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated - bs-6422R-A594 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CATSPER4 Antibody,Biotin conjugated - CSB-PA745763LD01HU from Cusabio

Host Rabbit
Clonality Polyclonal
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