RNF19A

Gene Symbol RNF19A
Entrez Gene 25897
Alt Symbol RNF19
Species Human
Gene Type protein-coding
Description ring finger protein 19A, RBR E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase RNF19A|double ring-finger protein|protein p38 interacting with transcription factor Sp1|ring finger protein 19|ring finger protein 19A, E3 ubiquitin protein ligase|ring-IBR-ring domain containing protein Dorfin
Swissprots Q9UFG0 Q9NV58 Q9H8M8 Q9UFX6 Q9H5H9 Q52LG1 A3KCU9 Q9Y4Y1
Accessions EAW91807 Q9NV58 AB029316 BAB39353 AB271913 BAF48116 AB271914 BAF48117 AJ242975 CAB45132 AK023455 BAB14581 AK027070 BAB15647 AK057699 AL110253 CAB53700 AL122096 CAB59264 AL708565 BC043648 AAH43648 BC062676 BC093938 AAH93938 BC093940 AAH93940 BC105300 AAI05301 BQ003778 DA502897 DB037264 DB061830 XM_005250853 XP_005250910 XM_011516956 XP_011515258 XR_928315 XR_928316 NM_001280539 NP_001267468 NM_015435 NP_056250 NM_183419 NP_904355
Function E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection. {ECO:0000269|PubMed:11237715, ECO:0000269|PubMed:12145308, ECO:0000269|PubMed:12750386, ECO:0000269|PubMed:15456787, ECO:0000269|PubMed:16513638}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:11237715, ECO:0000269|PubMed:12145308, ECO:0000269|PubMed:12750386, ECO:0000269|PubMed:15456787}. Note=Present in the hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients.
Tissue Specificity Widely expressed, with highest levels in heart. Ubiquitously expressed in the central nervous system. {ECO:0000269|PubMed:11237715}.

E3 ubiquitin-protein ligase RNF19A (RNF19A), Human, ELISA Kit - E01E0393 from ARP American Research Products

Category ELISA Kit
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Sizes 48 t, 96 t

E3 ubiquitin protein ligase RNF19A (RNF19A), ELISA Kit - MBS7236291 from MyBioSource

Category ELISA Kit
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Category ELISA Kit
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E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7217161 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7212571 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7249457 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7245375 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7213418 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7208833 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7200147 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7248810 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7230395 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7237564 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

E3 ubiquitin-protein ligase RNF19A (RNF19A), ELISA Kit - MBS7213037 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human RNF19A ELISA Kit - E012638 from Biobool

Category ELISA Kit
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