GRM3

Gene Symbol GRM3
Entrez Gene 2913
Alt Symbol GLUR3, GPRC1C, MGLUR3, mGlu3
Species Human
Gene Type protein-coding
Description glutamate receptor, metabotropic 3
Other Description glutamate metabotropic receptor 3|metabotropic glutamate receptor 3
Swissprots Q8TBH9 Q86YG6 Q75N17 Q75MV4 Q2PNZ6 Q14832
Accessions AAC60379 AAD15616 EAL24182 EAW76971 EAW76972 Q14832 AK291406 BAF84095 AK294178 BAH11690 AK294701 BAH11851 BC022496 AAH22496 BC041407 AAH41407 DQ315361 ABC47402 DQ315362 DQ315363 DQ892396 ABM83322 DQ893287 ABM84213 DQ896619 ABM87618 EU432123 ABY87922 X77748 CAA54796 XM_011516088 XP_011514390 XM_011516089 XP_011514391 XM_011516090 XP_011514392 NM_000840 NP_000831
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:8840013}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:8840013}; Multi-pass membrane protein {ECO:0000269|PubMed:8840013}.
Tissue Specificity Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala. {ECO:0000269|PubMed:8840013}.
Top Pathways Glutamatergic synapse, Cocaine addiction, Neuroactive ligand-receptor interaction

mGluR-3 (A-10) - sc-271899 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
mGluR-3 (A-10): sc-271899. Western blot analysis of mGluR-3 expression in HEK293 whole cell lysate.

mGluR-3 (E-12) - sc-47137 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

mGluR-3 (G-18) - sc-47138 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
mGluR-3 (G-18): sc-47138. Western blot analysis of mGluR-3 expression in 293T whole cell lysate.

mGluR-3 (H-50) - sc-99042 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

mGluR-3 (N-12) - sc-47139 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 3 antibody - ab140741 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Metabotropic Glutamate Receptor 3 staining in mouse brain formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab140741, 5µg/ml, for 15 mins at room temperature. A goat anti-rabbit biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Metabotropic Glutamate Receptor 3 antibody - ab196870 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Metabotropic Glutamate Receptor 3 antibody (ab196870) at 1/500 dilutionLane 1 : Raji cell line extractLane 2 : Mouse brain tissue extract

Anti-Metabotropic Glutamate Receptor 3 antibody - ab128252 from Abcam

Prices $372.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 3 antibody - ab187534 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Metabotropic Glutamate Receptor 3 antibody (ab187534) at 1/500 dilutionLane 1 : Raji cell extractLane 2 : Mouse brain cell extract

Anti-Metabotropic Glutamate Receptor 3 antibody - ab153671 from Abcam

Prices $370.00
Sizes 500 µl
Host Chicken
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 3 antibody - ab10309 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Metabotropic Glutamate Receptor 3 antibody - ab167464 from Abcam

Prices $376.00
Sizes 100 µl
Host Chicken
Clonality Polyclonal
Immunohistochemistry analysis of Formaldehyde/methanol-fixed Adult mouse cochlear ganglions labeling Metabotropic Glutamate Receptor 3 with ab167464 at 1/100 (red); DAPI staining (blue).

Anti-Metabotropic Glutamate Receptor 3 antibody [EPR9009(2)] - ab166608 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9009(2)
Anti-Metabotropic Glutamate Receptor 3 antibody [EPR9009(2)] (ab166608) at 1/1000 dilution + fetal brain lysate at 10 µgSecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Metabotropic Glutamate Receptor 3 antibody - C-terminal - ab137853 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Metabotropic Glutamate Receptor 3 antibody - C-terminal (ab137853) at 1/500 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Metabotropic Glutamate Receptor 3 antibody - N-terminal - ab188750 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry of HEK293 Human embryonic kidney cells transfected with Metabotropic Glutamate Receptor 3 using ab188750 at 10ug/ml.

Anti-GRM3 / MGLUR3 Antibody - LS-C342205 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GRM3 / MGLUR3 Antibody (N-Terminus) IHC-plus™ - LS-A899 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GRM3 / MGLUR3 Antibody (N-Terminus) IHC-plus™ - LS-A3208 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRM3 / MGLUR3 antibody LS-A3208 IHC of human brain, coroid plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GRM3 / MGLUR3 Antibody (aa118-126) - LS-C16537 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM3 / MGLUR3 Antibody - LS-C129281 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-GRM3 / MGLUR3 Antibody (C-Terminus) - LS-C145187 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM3 / MGLUR3 Antibody (C-Terminus) - LS-C153488 from LifeSpan Bioscience

Prices $305.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM3 / MGLUR3 Antibody (aa833-863, AP) - LS-C263041 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM3 / MGLUR3 Antibody (aa833-863, APC) - LS-C263043 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRM3 / MGLUR3 Antibody (aa833-863, FITC) - LS-C263045 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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