GRM3

Gene Symbol	GRM3
Entrez Gene	2913
Alt Symbol	GLUR3, GPRC1C, MGLUR3, mGlu3
Species	Human
Gene Type	protein-coding
Description	glutamate receptor, metabotropic 3
Other Description	glutamate metabotropic receptor 3|metabotropic glutamate receptor 3
Swissprots	Q8TBH9 Q86YG6 Q75N17 Q75MV4 Q2PNZ6 Q14832
Accessions	AAC60379 AAD15616 EAL24182 EAW76971 EAW76972 Q14832 AK291406 BAF84095 AK294178 BAH11690 AK294701 BAH11851 BC022496 AAH22496 BC041407 AAH41407 DQ315361 ABC47402 DQ315362 DQ315363 DQ892396 ABM83322 DQ893287 ABM84213 DQ896619 ABM87618 EU432123 ABY87922 X77748 CAA54796 XM_011516088 XP_011514390 XM_011516089 XP_011514391 XM_011516090 XP_011514392 NM_000840 NP_000831
Function	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:8840013}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:8840013}; Multi-pass membrane protein {ECO:0000269|PubMed:8840013}.
Tissue Specificity	Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala. {ECO:0000269|PubMed:8840013}.
Top Pathways	Glutamatergic synapse, Cocaine addiction, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Metabotropic Glutamate Receptor 3 protein fragment - ab114583 from Abcam Category Protein Source Wheat germ Species Human

GRM3 / MGLUR3 Antibody Blocking Peptide - LS-E28703 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM3 / MGLUR3 Antibody Blocking Peptide - LS-E28705 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GRM3 / MGLUR3 Antibody Blocking Peptide - LS-E29533 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human mGluR3 Protein - H00002913-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human mGluR3 Protein - H00002913-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

mGluR3 / GRM3 - H00002913-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

mGluR3 / GRM3 - H00002913-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

mGluR3 / GRM3 - H00002913-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

GRM3 fusion protein - ag4794 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GRM3 fusion protein - Ag5306 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human GRM3 - GRM3-29609TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Glutamate Receptor, Metabotropic 3 (GRM3) - RPB891Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Glutamate Receptor, Metabotropic 3 Protein (Recombinant) - abx167009 from Abbexa Category Protein Source Human Species Human

Recombinant Human GRM3 protein - GRM3-29610TH from Creative Biomart Category Protein Source Wheat Germ Species Human

Metabotropic-Glutamate-Receptor-3-Antibody-C-term-Blocking-peptide - BP6343a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GRM3 Peptide, Human - M34GP06675H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Glutamate Receptor, Metabotropic 3 (GRM3) - RPU53071 from Biomatik Category Protein Prices $194.00, $396.00, $605.00, $721.60 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

GRM3 Recombinant Protein (OPCD03689) - OPCD03689 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant Human mGluR3 Protein, CF - 9527-UR from R&D Systems Category Protein Prices $599.00 Sizes 100 µg Source Chinese Hamster Ovary cell line, CHO-derived Asp25-Ser507, with a C-terminal 6-His tag Species Human

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