GRM3

Gene Symbol GRM3
Entrez Gene 2913
Alt Symbol GLUR3, GPRC1C, MGLUR3, mGlu3
Species Human
Gene Type protein-coding
Description glutamate receptor, metabotropic 3
Other Description glutamate metabotropic receptor 3|metabotropic glutamate receptor 3
Swissprots Q8TBH9 Q86YG6 Q75N17 Q75MV4 Q2PNZ6 Q14832
Accessions AAC60379 AAD15616 EAL24182 EAW76971 EAW76972 Q14832 AK291406 BAF84095 AK294178 BAH11690 AK294701 BAH11851 BC022496 AAH22496 BC041407 AAH41407 DQ315361 ABC47402 DQ315362 DQ315363 DQ892396 ABM83322 DQ893287 ABM84213 DQ896619 ABM87618 EU432123 ABY87922 X77748 CAA54796 XM_011516088 XP_011514390 XM_011516089 XP_011514391 XM_011516090 XP_011514392 NM_000840 NP_000831
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:8840013}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:8840013}; Multi-pass membrane protein {ECO:0000269|PubMed:8840013}.
Tissue Specificity Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala. {ECO:0000269|PubMed:8840013}.
Top Pathways Glutamatergic synapse, Cocaine addiction, Neuroactive ligand-receptor interaction

mGluR-3 CRISPR/Cas9 KO Plasmid (h) - sc-404012 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 HDR Plasmid (h) - sc-404012-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 Double Nickase Plasmid (h) - sc-404012-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 Double Nickase Plasmid (h2) - sc-404012-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 CRISPR Activation Plasmid (h) - sc-404012-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 CRISPR Activation Plasmid (h2) - sc-404012-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 Lentiviral Activation Particles (h) - sc-404012-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 Lentiviral Activation Particles (h2) - sc-404012-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

mGluR-3 siRNA (h) - sc-61030 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR-3 shRNA Plasmid (h) - sc-61030-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR-3 shRNA (h) Lentiviral Particles - sc-61030-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

mGluR3 RNAi - H00002913-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU126661 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9703 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9703 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04225 from Sigma-Aldrich

Category miRNA

GRM3 siRNA (Human) - CRH1966 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRM3 - MBS8216726 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GRM3 (NM_000840.2) - SHH308114 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GRM3(NM_000840.2) - SHH105581 from Creative biogene

Category siRNA
Species Reactivities Human

Human GRM3 siRNA - orb262468 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GRM3 shRNA Plasmid (Human) - CHH1966 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GRM3 miRNA 3'UTR clone - MiUTR1H-04291 from Creative biogene

Species Reactivities Human
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