CBFA2T2

Gene Symbol CBFA2T2
Entrez Gene 9139
Alt Symbol EHT, MTGR1, ZMYND3, p85
Species Human
Gene Type protein-coding
Description core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Other Description ETO homolog on chromosome 20|ETO homologous on chromosome 20|MTG8-like protein|MTG8-related protein 1|myeloid translocation gene-related protein 1|myeloid translocation-related protein 1|protein CBFA2T2
Swissprots O43439 Q5TGE7 Q5TGE4 F8W6D7 Q96L00 Q5TGE5 Q9UJP8 Q9H436 Q96B06 B2RAE6 Q5TGE6 Q9UP24 Q9UJP9 Q8IWF3
Accessions AAD41221 CCQ43298 EAW76311 EAW76312 EAW76313 O43439 AB209306 BAD92543 AF013970 AAC39841 AF039200 AAC17499 AF052210 AAC64699 AF052211 AAC64700 AF052212 AF068266 AAC19378 AF069747 AAD02825 AK294168 BAG57490 AK307887 AK314159 BAG36843 BC015066 AAH15066 BC016298 AAH16298 BC040344 AAH40344 CB998035 CN347014 CR749462 CAH18294 EU446928 ABZ92457 JF432662 ADZ15879 XM_006723886 XP_006723949 XM_011529101 XP_011527403 XM_011529102 XP_011527404 XM_011529103 XP_011527405 XM_011529104 XP_011527406 XM_011529105 XP_011527407 XM_011529106 XP_011527408 XM_011529107 XP_011527409 NM_001032999 NP_001028171 NM_001039709 NP_001034798 NM_005093 NP_005084 NM_175864
Function May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Ubiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus. {ECO:0000269|PubMed:10675041, ECO:0000269|PubMed:9447981, ECO:0000269|PubMed:9787195, ECO:0000269|PubMed:9790752}.

MTGR1 (B-7) - sc-390114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MTGR1 (B-7): sc-390114. Western blot analysis of MTGR1 expression in Jurkat (A) and HeLa (B) nuclear extracts.

MTGR1 (H-68) - sc-366301 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MTGR1 (H-68): sc-366301. Western blot analysis of MTGR1 expression in Jurkat (A) and HeLa (B) nuclear extracts and mouse testis (C), rat thymus (D) and mouse colon (E) tissue extracts.

MTGR1 (P-17) - sc-55967 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MTGR1 (P-17): sc-55967. Western blot analysis of MTGR1 expression in Jurkat nuclear extract.

MTGR1 (L-18) - sc-55966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MTGR1 (L-18): sc-55966. Western blot analysis of MTGR1 expression in Jurkat nuclear extract.

MTGR1 (CBF5I134) - sc-81326 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
ZnT-9 (919C1a): sc-81118 Western Blot analysis of human recombinant ZnT-9 fusion protein.

Anti-MTGR1 antibody - ab96161 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MTGR1 antibody (ab96161) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-MTGR1 antibody - ab124152 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MTGR1 antibody (ab124152) at 1/100 dilution + Jurkat cell lysate at 35 µg

Anti-MTGR1 antibody - ab16137 from Abcam

Prices $370.00
Sizes 250 µg
Host Sheep
Clonality Polyclonal

Anti-MTGR1 antibody [CBF5I134] - ab51311 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CBF5I134
Anti-MTGR1 antibody [CBF5I134] (ab51311) at 1/50 dilution + HeLa whole cell lysate at 25 µgSecondaryanti-mouse IgG at 1/2500 dilutiondeveloped using the ECL technique

Anti-CBFA2T2 / MTGR1 Antibody (C-Terminus) IHC-plus™ - LS-B11988 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-CBFA2T2 / MTGR1 Antibody - LS-C26559 from LifeSpan Bioscience

Prices $330.00
Sizes 250 µg
Host Sheep
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody - LS-C79757 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-CBFA2T2 / MTGR1 Antibody - LS-C130833 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-CBFA2T2 / MTGR1 Antibody (clone KT42) - LS-C193501 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone KT42

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, APC) - LS-C253470 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, AP) - LS-C253469 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, Biotin) - LS-C253471 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (aa357-406) - LS-C30097 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NIH 3T3 Cell Lysate

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, FITC) - LS-C253472 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, Azide-free, HRP) - LS-C253473 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30, PE) - LS-C253474 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (aa1-30) - LS-C329321 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody - LS-C306753 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-CBFA2T2 / MTGR1 Antibody (N-Terminus) - LS-C80217 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CBFA2T2 / MTGR1 Antibody (aa361-410) - LS-C116116 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CBFA2T2 antibody LS-C116116 Western blot of Mouse Brain lysate.
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