CBFA2T2

Gene Symbol CBFA2T2
Entrez Gene 9139
Alt Symbol EHT, MTGR1, ZMYND3, p85
Species Human
Gene Type protein-coding
Description core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Other Description ETO homolog on chromosome 20|ETO homologous on chromosome 20|MTG8-like protein|MTG8-related protein 1|myeloid translocation gene-related protein 1|myeloid translocation-related protein 1|protein CBFA2T2
Swissprots O43439 Q5TGE7 Q5TGE4 F8W6D7 Q96L00 Q5TGE5 Q9UJP8 Q9H436 Q96B06 B2RAE6 Q5TGE6 Q9UP24 Q9UJP9 Q8IWF3
Accessions AAD41221 CCQ43298 EAW76311 EAW76312 EAW76313 O43439 AB209306 BAD92543 AF013970 AAC39841 AF039200 AAC17499 AF052210 AAC64699 AF052211 AAC64700 AF052212 AF068266 AAC19378 AF069747 AAD02825 AK294168 BAG57490 AK307887 AK314159 BAG36843 BC015066 AAH15066 BC016298 AAH16298 BC040344 AAH40344 CB998035 CN347014 CR749462 CAH18294 EU446928 ABZ92457 JF432662 ADZ15879 XM_006723886 XP_006723949 XM_011529101 XP_011527403 XM_011529102 XP_011527404 XM_011529103 XP_011527405 XM_011529104 XP_011527406 XM_011529105 XP_011527407 XM_011529106 XP_011527408 XM_011529107 XP_011527409 NM_001032999 NP_001028171 NM_001039709 NP_001034798 NM_005093 NP_005084 NM_175864
Function May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Ubiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus. {ECO:0000269|PubMed:10675041, ECO:0000269|PubMed:9447981, ECO:0000269|PubMed:9787195, ECO:0000269|PubMed:9790752}.

Human MTGR1 full length protein - ab152954 from Abcam

Category Protein
Source Wheat germ
Species Human
ab152954 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human MTGR1 protein fragment - ab152955 from Abcam

Category Protein
Source Wheat germ
Species Human
ab152955 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CBFA2T2 / MTGR1 Antibody Blocking Peptide - LS-E4027 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CBFA2T2 / MTGR1 Antibody Blocking Peptide - LS-E25145 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CBFA2T2 / MTGR1 Antibody Blocking Peptide - LS-E13872 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CBFA2T2 / MTGR1 Antibody Blocking Peptide - LS-E13873 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CBFA2T2 / MTGR1 Antibody Blocking Peptide - LS-E13458 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human MTGR1 Protein - H00009139-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human MTGR1 Protein - H00009139-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

CBFA2T2-Antibody-N-term-Blocking-Peptide - BP16252a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CBFA2T2 - H00009139-P01-02 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Source in vitro transl.
Species Human

CBFA2T2 - H00009139-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

CBFA2T2 - H00009139-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

CBFA2T2 fusion protein - ag1880 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human Protein CBFA2T2(CBFA2T2) - CSB-YP004575HU CSB-EP004575HU CSB-BP004575HU CSB-MP004575HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CBFA2T2 (transcript variant 4) - TP302013 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
CBFA2T2

MTGR1 Recombinant Protein Antigen - NBP2-34136PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CBFA2T2 Peptide, Human - M34GP02418H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

MTGR1 Recombinant Protein Antigen - NBP2-56057PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Protein CBFA2T2 (CBFA2T2), Recombinant Protein - MBS1059343 from MyBioSource

Category Protein
Prices $1,395.00, $1,395.00, $1,625.00, $1,625.00, $2,355.00, $2,355.00, $2,800.00, $2,800.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
Search more