Hdac2

Gene Symbol	Hdac2
Entrez Gene	15182
Alt Symbol	D10Wsu179e, YAF1, Yy1bp, mRPD3
Species	Mouse
Gene Type	protein-coding
Description	histone deacetylase 2
Other Description	HD2|YY1 transcription factor-binding protein
Swissprots	B2RRP3 P70288
Accessions	EDL04897 P70288 AB221663 AK051753 BAC34755 AK135572 BAE22585 AK141649 BAE24786 AK165734 BAE38360 BC138517 AAI38518 U31758 AAC52889 XM_006512555 XP_006512618 NM_008229 NP_032255
Function	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA- replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. May be involved in the transcriptional repression of circadian target genes, such as PER1, mediated by CRY1 through histone deacetylation. I
Subcellular Location	Nucleus. Cytoplasm {ECO:0000250}.
Top Pathways	Viral carcinogenesis, Alcoholism, Epstein-Barr virus infection, Cell cycle, Huntington's disease

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Mouse HDAC2 ELISA Kit (Sandwich ELISA) - LS-F7515 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 0.055 ng/ml Range 0.156-10 ng/ml

Histone Deacetylase 2, Mouse, ELISA Kit - E03H0235 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Mouse HDAC2(Histone Deacetylase 2) ELISA Kit - E-EL-M0120 from Elabscience Category ELISA Kit Sensitivity 0.10 ng/mL Range 0.16—10 ng/mL

Mouse HDAC2 (Histone Deacetylase 2) CLIA Kit - E-CL-M0093 from Elabscience Category CLIA Kit Sensitivity 18.75 pg/mL Range Average Recovery (%)

histone deacetylase 2 (Hdac2/Yy1bp) , ELISA Kit - MBS9310735 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mouse Histone Deacetylase 2 (HDAC2) ELISA Kit - EKU04815 from Biomatik Category ELISA Kit Prices $756.00, $3,326.00, $6,048.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.055 ng/mL Range 0.156-10 ng/mL

Mouse HDAC2 (Histone Deacetylase 2) CLIA Kit - E-CL-M0093 from Iwai North America Inc. Category CLIA Kit Prices $722.50 Sizes 1 kit Sensitivity 0.094ng/mL Range 0.156-10ng/mL

Mouse Histone Deacetylase 2 ELISA Kit - abx254165 from Abbexa Category ELISA Kit Sensitivity 0.094 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse Histone Deacetylase 2 ELISA Kit - abx154144 from Abbexa Category ELISA Kit Sensitivity 0.073 ng/ml Range 0.156 ng/ml - 10 ng/ml

Mouse HDAC2 ELISA Kit (Sandwich ELISA) - LS-F21306 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.094 ng/ml Range 0.156-10 ng/ml

HDAC2 - EKM2222 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156--10ng/ml

Mouse Hdac2 ELISA Kit - E055212 from Biobool Category ELISA Kit Sensitivity 0.094ng/mL

Mouse Hdac2/Yy1bp ELISA Kit - E055863 from Biobool Category ELISA Kit

HDAC2 ELISA Kit (Mouse) (OKDD00723) - OKDD00723 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity <0.073 ng/mL Range 0.156-10 ng/mL

Histone Deacetylase 2 (HDAC2), ELISA Kit - MBS452847 from MyBioSource Category ELISA Kit Prices $425.00, $560.00, $2,480.00, $4,820.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.073ng/mL Range 0.156-10ng/mL

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