Gene Symbol | PPAP2C |
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Entrez Gene | 8612 |
Alt Symbol | LPP2, PAP-2c, PAP2-g |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidic acid phosphatase type 2C |
Other Description | PAP2-gamma|PAP2c|lipid phosphate phosphohydrolase 2|phosphatidate phosphohydrolase type 2c|phosphatidic acid phosphatase 2c|phosphatidic acid phosphohydrolase type 2c|type-2 phosphatidic acid phosphatase-gamma |
Swissprots | E9PAY8 A6NLV0 O43688 |
Accessions | EAW61207 EAW61208 EAW61209 O43688 AA428937 AB209696 BAD92933 AF035959 AAC15968 AF047760 AAC32104 AF056083 AAC25666 BC002806 AAH02806 BE615792 BG831889 BM050291 BM982485 BT007021 AAP35667 HY160303 XM_011528396 XP_011526698 NM_003712 NP_003703 NM_177526 NP_803545 NM_177543 NP_808211 |
Function | Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P). The relative catalytic efficiency is PA > C-1-P > LPA > S-1-P. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Found mainly in brain, pancreas and placenta. |
Top Pathways | Fc gamma R-mediated phagocytosis, Fat digestion and absorption, Choline metabolism in cancer, Ether lipid metabolism, Glycerolipid metabolism |
PAP-2c (C-18) - sc-51400 from Santa Cruz Biotechnology
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PAP-2c (E-15) - sc-51401 from Santa Cruz Biotechnology
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PAP-2c (F-16) - sc-51402 from Santa Cruz Biotechnology
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PAP-2c (H-80) - sc-367327 from Santa Cruz Biotechnology
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Anti-PPAP2C antibody - ab199266 from Abcam
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Anti-PPAP2C Antibody - LS-C26762 from LifeSpan Bioscience
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Anti-PPAP2C Antibody - LS-C26805 from LifeSpan Bioscience
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Anti-PPAP2C Antibody (aa227-254) - LS-C97286 from LifeSpan Bioscience
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PPAP2C Antibody - NBP2-31607 from Novus Biologicals
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Rabbit Anti-PPAP2C Polyclonal Antibody - bs-5433R from Bioss
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LPP2 Polyclonal Antibody - bs-8527R from Bioss
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Anti-Lipid Phosphate Phosphatase 2 (LPP2) antibody produced in rabbit - L2790 from Sigma-Aldrich
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ANTI-PPAP2C (C-TERM) antibody produced in rabbit - SAB1303858 from Sigma-Aldrich
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PPAP2C Antibody - C-terminal region (OAAB01506) - OAAB01506 from Aviva Systems Biology
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PPAP2C-Antibody-C-term - AP2799b from Abgent, a WuXi AppTec company
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PPAP2C antibody - orb6642 from Biorbyt
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PPAP2C / LPP2 antibody - AP05145PU-N from Acris Antibodies
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PPAP2C / LPP2 antibody - AP05175PU-N from Acris Antibodies
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PPAP2C / LPP2 (C-term) antibody - AP12449PU-N from Acris Antibodies
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PPAP2C / LPP2 antibody - PAB10122 from Acris Antibodies
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PPAP2C antibody - 10451-1-AP from Proteintech Group
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PAP2c Antibody - 251258 from ABBIOTEC
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PPAP2C Antibody - 37206 from Signalway Antibody
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Lipid Phosphate Phosphohydrolase 2, Polyclonal Antibody - MBS395724 from MyBioSource
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Lyosphospholipid Phosphatase (LPP) 2, Polyclonal Antibody - MBS395992 from MyBioSource
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