SNAPIN

Gene Symbol	SNAPIN
Entrez Gene	23557
Alt Symbol	BLOC1S7, BLOS7, SNAPAP
Species	Human
Gene Type	protein-coding
Description	SNAP-associated protein
Other Description	BLOC-1 subunit 7|SNAP-25-binding protein|SNARE associated protein snapin|SNARE-associated protein Snapin|biogenesis of lysosomal organelles complex-1, subunit 7|biogenesis of lysosome-related organelles complex 1 subunit 7|synaptosomal-associated protein 25-binding protein
Swissprots	Q5SXU8 O95295 D3DV56
Accessions	CAI18797 EAW53288 EAW53289 O95295 AA173972 AF086837 AAD11417 AI018675 AK024555 BAB14927 BC000761 AAH00761 BC004494 AAH04494 BE278772 BI117540 BM051828 BT006753 AAP35399 CD671119 NM_012437 NP_036569 NR_052019 NR_052020
Function	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma- membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells. {ECO:000
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:18167355, ECO:0000269|PubMed:19168546, ECO:0000269|PubMed:21102408}. Golgi apparatus membrane {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=May be cytoplasmic and peripheral membrane bound or anchored to the vesicular membrane through an N- terminal signal anchor (By similarity). Colocalizes with NANOS1 and PUM2 in the perinuclear region of germ cells. {ECO:0000250}.
Tissue Specificity	Expressed in male germ cells of adult testis (at protein level). {ECO:0000269|PubMed:19168546}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNAPIN ELISA Kit (Sandwich ELISA) - LS-F9014 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.066 ng/ml Range 0.156-10 ng/ml

SNAP Associated Protein (SNAPAP), Human, ELISA Kit - SEH163Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.066ng/mL Range 0.156-10ng/mL

SNARE-associated protein Snapin (SNAPIN), Human, ELISA Kit - CSB-EL021882HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

SNAP Associated Protein (SNAPAP), ELISA Kit - MBS2022613 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human SNAPAP is typically less than 0.066ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

SNAP-associated protein, ELISA Kit - MBS914564 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 8 pg/ml Range 32 pg/ml-1200 pg/ml

ELISA Kit for SNAP Associated Protein (SNAPAP) - SEH163Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.066ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human SNARE-associated protein Snapin(SNAPIN) ELISA kit - CSB-EL021882HU from Cusabio Category ELISA Kit Sensitivity 8pg/ml Range 32 pg/ml-1200 pg/ml

ELISA Kit for SNAP Associated Protein (SNAPAP) - SEH163Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.066ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human SNAPAP ELISA Kit - abx153128 from Abbexa Category ELISA Kit Sensitivity 0.066 ng/ml Range 0.156 ng/ml - 10 ng/ml

SNAP Associated Protein (SNAPAP), Human, ELISA Kit - DL-SNAPAP-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human SNAPAP ELISA Kit - orb370511 from Biorbyt Category ELISA Kit Prices $553.00, $621.00 Sizes 48 test, 96 test Range Detection Range: 0.156-10ng/mL Detection low threshold: 0.066ng/mL

Human SNAPAP ELISA Kit - abx571632 from Abbexa Category ELISA Kit Sensitivity 0.066 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human SNAPAP ELISA Kit - E035562 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of human SNAPAP is typically less than 0.066ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by ad

Human SNAPIN ELISA Kit - E035563 from Biobool Category ELISA Kit Sensitivity 8 pg/ml

SNAPIN ELISA Kit (Human) (OKCD00523) - OKCD00523 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.066 ng/mL Range 0.156-10 ng/mL

SNAPAP ELISA Kit (Human) (OKDD00535) - OKDD00535 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.066 ng/mL Range 0.156-10 ng/mL

SNAP Associated Protein (SNAPAP), ELISA Kit - MBS454414 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.066ng/mL Range 0.156-10ng/mL

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