SNAPIN

Gene Symbol	SNAPIN
Entrez Gene	23557
Alt Symbol	BLOC1S7, BLOS7, SNAPAP
Species	Human
Gene Type	protein-coding
Description	SNAP-associated protein
Other Description	BLOC-1 subunit 7|SNAP-25-binding protein|SNARE associated protein snapin|SNARE-associated protein Snapin|biogenesis of lysosomal organelles complex-1, subunit 7|biogenesis of lysosome-related organelles complex 1 subunit 7|synaptosomal-associated protein 25-binding protein
Swissprots	Q5SXU8 O95295 D3DV56
Accessions	CAI18797 EAW53288 EAW53289 O95295 AA173972 AF086837 AAD11417 AI018675 AK024555 BAB14927 BC000761 AAH00761 BC004494 AAH04494 BE278772 BI117540 BM051828 BT006753 AAP35399 CD671119 NM_012437 NP_036569 NR_052019 NR_052020
Function	Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma- membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells. {ECO:000
Subcellular Location	Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:18167355, ECO:0000269|PubMed:19168546, ECO:0000269|PubMed:21102408}. Golgi apparatus membrane {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle {ECO:0000250}. Note=May be cytoplasmic and peripheral membrane bound or anchored to the vesicular membrane through an N- terminal signal anchor (By similarity). Colocalizes with NANOS1 and PUM2 in the perinuclear region of germ cells. {ECO:0000250}.
Tissue Specificity	Expressed in male germ cells of adult testis (at protein level). {ECO:0000269|PubMed:19168546}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SNAPIN full length protein - ab81766 from Abcam Category Protein Source E. coli Species Human

Snapin Recombinant Protein - H00023557-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Snapin Partial Recombinant Protein - H00023557-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Snapin Protein - NBC1-22575 from Novus Biologicals Category Protein Prices $229.00 Sizes 100 µg Source E.coli Species Human

SNAPIN Protein (OPPA01848) - OPPA01848 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 10 µg Source E. Coli

Human SNAP Associated protein - orb81373 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 10 μg, 50 μg Source E.coli

SNAPAP protein (His tag) - 80R-1097 from Fitzgerald Category Protein Prices $180.00 Sizes 100 µg Source E.coli

SNAPIN (1-136, His-tag) - AR50028PU-N from Acris Antibodies Category Protein Prices $590.00 Sizes 500 µg Source E. coli Species Human

SNAPIN (1-136, His-tag) - AR50028PU-S from Acris Antibodies Category Protein Prices $270.00 Sizes 100 µg Source E. coli Species Human

SNAPIN - H00023557-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SNAPIN - H00023557-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SNAPIN - H00023557-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SNAPIN - H00023557-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SNAP Associated Protein, Human Recombinant - 228-11442-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human SNAPIN - 228-11442-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human SNAPIN - 228-11442-3 from RayBiotech Category Protein Prices $1,950.00 Sizes 3 µg Source Escherichia Coli. Species Human

SNAPAP, 1-136aa, Human, His tagged, Recombinant, E.coli - 01-2037 from ARP American Research Products Category Protein Prices $139.00, $299.00, $639.00 Sizes 20 µg, 100 µg, 500 µg Source E.coli Species Human

SNAPIN fusion protein - Ag5978 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

SNAPIN fusion protein - Ag0101 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SNAP Associated Protein - BP002042-PRO-663 from Syd Labs Category Protein Prices $160.00, $1,800.00 Sizes 50 µg, 1 mg Source E. coli-derived. Species Human

SNAPAP, 1-136aa, Recombinant Protein - GWB-P0051L from Genway Biotech Category Protein Prices $210.00, $630.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human SNAP Associated Protein - GWB-A09436 from Genway Biotech Category Protein Prices $75.00, $165.00, $1,195.00 Sizes 10 μg, 50 μg, 1000 μg Species Human

Recombinant Human SNAP-associated Protein - SNAPIN-307H from Creative Biomart Category Protein Source E.coli.

Recombinant Human SNAPIN, His-tagged - SNAPIN-30508TH from Creative Biomart Category Protein Source E. coli

Recombinant Human SNAPIN, His-tagged - SNAPIN-30509TH from Creative Biomart Category Protein Source E. coli

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