Gene Symbol |
NCR1
|
Entrez Gene |
9437
|
Alt Symbol |
CD335, LY94, NK-p46, NKP46
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
natural cytotoxicity triggering receptor 1
|
Other Description |
NK cell-activating receptor|lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46)|natural killer cell p46-related protein
|
Swissprots |
O76017 O76018 O76016 B0V3L5 B0V3L4 O76036 B0V3L2 B8JL03 B0V3L3
|
Accessions |
EAW72308 EAW72309 EAW72310 EAW72311 EAW72312 O76036 AJ001383 CAA04714 AJ006121 CAA06872 AJ006122 CAA06873 AJ006123 CAA06874 AY346373 AAQ54328 BC064806 AAH64806 HQ448088 ADQ32569 XM_011527528 XP_011525830 XM_011527529 XP_011525831 XM_011527530 XP_011525832 XM_011547125 XP_011545427 XM_011547126 XP_011545428 XM_011547127 XP_011545429 XM_011547535 XP_011545837 XM_011547536 XP_011545838 XM_011547537 XP_011545839 XM_011547798 XP_011546100 XM_011547799 XP_011546101 XM_011547800 XP_011546102 XM_011547993 XP_011546295 XM_011547994 XP_011546296 XM_011547995 XP_011546297 XM_011548172 XP_011546474 XM_011548173 XP_011546475 XM_011548174 XP_011546476 XM_011548364 XP_011546666 XM_011548365 XP_011546667 XM_011548366 XP_011546668 XM_011548571 XP_011546873 XM_011548572 XP_011546874 XM_011548573 XP_011546875 XM_011548629 XP_011546931 XM_011548630 XP_011546932 XM_011548631 XP_011546933 XM_011548718 XP_011547020 XM_011548719 XP_011547021 XM_011548720 XP_011547022 NM_001145457 NP_001138929 NM_001145458 NP_001138930 NM_001242356 NP_001229285 NM_001242357 NP_001229286 NM_004829 NP_004820
|
Function |
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000269|PubMed:9730896}.
|
Subcellular Location |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
Tissue Specificity |
Selectively expressed by both resting and activated NK cells. {ECO:0000269|PubMed:9730896}.
|
Top Pathways |
Natural killer cell mediated cytotoxicity
|