NCR1

Gene Symbol	NCR1
Entrez Gene	9437
Alt Symbol	CD335, LY94, NK-p46, NKP46
Species	Human
Gene Type	protein-coding
Description	natural cytotoxicity triggering receptor 1
Other Description	NK cell-activating receptor|lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46)|natural killer cell p46-related protein
Swissprots	O76017 O76018 O76016 B0V3L5 B0V3L4 O76036 B0V3L2 B8JL03 B0V3L3
Accessions	EAW72308 EAW72309 EAW72310 EAW72311 EAW72312 O76036 AJ001383 CAA04714 AJ006121 CAA06872 AJ006122 CAA06873 AJ006123 CAA06874 AY346373 AAQ54328 BC064806 AAH64806 HQ448088 ADQ32569 XM_011527528 XP_011525830 XM_011527529 XP_011525831 XM_011527530 XP_011525832 XM_011547125 XP_011545427 XM_011547126 XP_011545428 XM_011547127 XP_011545429 XM_011547535 XP_011545837 XM_011547536 XP_011545838 XM_011547537 XP_011545839 XM_011547798 XP_011546100 XM_011547799 XP_011546101 XM_011547800 XP_011546102 XM_011547993 XP_011546295 XM_011547994 XP_011546296 XM_011547995 XP_011546297 XM_011548172 XP_011546474 XM_011548173 XP_011546475 XM_011548174 XP_011546476 XM_011548364 XP_011546666 XM_011548365 XP_011546667 XM_011548366 XP_011546668 XM_011548571 XP_011546873 XM_011548572 XP_011546874 XM_011548573 XP_011546875 XM_011548629 XP_011546931 XM_011548630 XP_011546932 XM_011548631 XP_011546933 XM_011548718 XP_011547020 XM_011548719 XP_011547021 XM_011548720 XP_011547022 NM_001145457 NP_001138929 NM_001145458 NP_001138930 NM_001242356 NP_001229285 NM_001242357 NP_001229286 NM_004829 NP_004820
Function	Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000269|PubMed:9730896}.
Subcellular Location	Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity	Selectively expressed by both resting and activated NK cells. {ECO:0000269|PubMed:9730896}.
Top Pathways	Natural killer cell mediated cytotoxicity

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NCR1 full length protein - ab132141 from Abcam Category Protein Source Wheat germ Species Human

Human NCR1 protein fragment - ab191681 from Abcam Category Protein Source HEK 293 cells Species Human

NCR1 protein fragment - ab51221 from Abcam Category Protein Source E. coli

NCR1 / NKP46 Antibody Blocking Peptide - LS-E23223 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCR1 / NKP46 Antibody Blocking Peptide - LS-E23224 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NKp46/NCR1 Recombinant Protein - H00009437-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NKp46/NCR1 Protein - NBC1-18414 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Species Human

NKp46/NCR1 Recombinant Protein - H00009437-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

Recombinant Human NKp46/NCR1 Fc Chimera, CF - 1850-NK-025 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

NKp46 Protein (OPPA01342) - OPPA01342 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human NKp46 protein - orb81235 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CD335 Blocking Peptide - abx063586 from Abbexa Category Peptide Species Human

CD335 / NKp46 (22-255) - SA6038 from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

CD335 / NKp46 (22-255) - SA6038X from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

CD335 / NKp46 - H00009437-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD335 / NKp46 - H00009437-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD335 / NKp46 - H00009437-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Natural Cytotoxicity Receptor NKp46, Human Recombinant - 228-11157-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human NKp46 - 228-11157-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human NKp46 - 228-11157-3 from RayBiotech Category Protein Prices $3,080.00 Sizes 3 µg Source Escherichia Coli. Species Human

NCR, NKp46 ( Extracellular Ig-like domain ; 22-255aa, human), Recombinant, E.coli - 01-2226 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Source E.coli Species Human

NCR1 Recombinant Protein - 96-550 from ProSci Category Protein Prices $425.00 Sizes 50 µg Source HEK293 cells Species Human

NCR1 fusion protein - ag6118 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NCR1 fusion protein - ag6454 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

NKp46 Human - PRPS-439 from NeoScientific Category Protein Prices $65.00, $169.00, $3,640.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

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