Plcg1

Gene Symbol Plcg1
Entrez Gene 18803
Alt Symbol AI894140, Cded, Plc-1, Plc-gamma1, Plcg-1
Species Mouse
Gene Type protein-coding
Description phospholipase C, gamma 1
Other Description 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1|PLC-gamma-1|cell differentiation and embryonic development|phosphoinositide phospholipase C-gamma-1|phospholipase C-gamma-1
Swissprots Q62077 Q6P1G1
Accessions AAX90611 CBF62965 CBF74731 CBU87841 CBU96788 EDL06290 EDL06291 EDL06292 Q62077 AF027185 AAD09344 AK134041 BAE21990 AK160731 BAE35976 AK162809 AK169695 BAE41310 AK169777 BAE41359 AK185701 BC057161 BC065091 AAH65091 X95346 CAA64639 NM_021280 NP_067255
Function Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. {ECO:0000269|PubMed:15308098}.
Subcellular Location Cell projection, lamellipodium {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. {ECO:0000250}.
Top Pathways Epstein-Barr virus infection, Proteoglycans in cancer, Rap1 signaling pathway, Choline metabolism in cancer, VEGF signaling pathway

PLCG1 antibody (Tyr783) - 70R-31041 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PLCG1 antibody (Tyr771) - 70R-31039 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PLCG1 antibody - 70R-31042 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PLCG1 antibody - 70R-31040 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PLCG1, Polyclonal Antibody - MBS2529592 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

PLCG1, Polyclonal Antibody - MBS2529626 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

PLCG1, Polyclonal Antibody - MBS2523233 from MyBioSource

Prices $110.00, $150.00, $225.00, $360.00
Sizes 20 µl, 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal

PLCg1 - MBS6003055 from MyBioSource

Prices $575.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

PLC gamma 1 antibody - 70R-50217 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLC gamma 1 antibody - 70R-50215 from Fitzgerald

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLC gamma 1 antibody - 70R-50216 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLCG1 antibody - 70R-51609 from Fitzgerald

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ARG51818 anti-PLC gamma1 phospho (Tyr771) antibody WB image Western Blot: extracts from 3T3 cells untreated or treated with serum stained with anti-PLC gamma1 (phospho Tyr771) antibody ARG51818.
ARG51605 anti-PLC gamma1 phospho (Tyr783) antibody WB image Western Blot: extracts from HL60 cells untreated or treated with EGF stained with anti-PLC gamma1 (phospho Tyr783) antibody ARG51605.
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