Plcg1

Gene Symbol Plcg1
Entrez Gene 18803
Alt Symbol AI894140, Cded, Plc-1, Plc-gamma1, Plcg-1
Species Mouse
Gene Type protein-coding
Description phospholipase C, gamma 1
Other Description 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1|1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1|PLC-gamma-1|cell differentiation and embryonic development|phosphoinositide phospholipase C-gamma-1|phospholipase C-gamma-1
Swissprots Q62077 Q6P1G1
Accessions AAX90611 CBF62965 CBF74731 CBU87841 CBU96788 EDL06290 EDL06291 EDL06292 Q62077 AF027185 AAD09344 AK134041 BAE21990 AK160731 BAE35976 AK162809 AK169695 BAE41310 AK169777 BAE41359 AK185701 BC057161 BC065091 AAH65091 X95346 CAA64639 NM_021280 NP_067255
Function Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. {ECO:0000269|PubMed:15308098}.
Subcellular Location Cell projection, lamellipodium {ECO:0000250}. Cell projection, ruffle {ECO:0000250}. Note=Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment. {ECO:0000250}.
Top Pathways Epstein-Barr virus infection, Proteoglycans in cancer, Rap1 signaling pathway, Choline metabolism in cancer, VEGF signaling pathway

SignalSilence ® PLCγ1 siRNA I (Mouse Specific) - 6413 from Cell Signaling Technology

Category siRNA
Prices $249.00
Sizes 300 µl (3 nmol)
Western blot analysis of extracts from C2C12 cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-) or SignalSilence ® PLCγ1 siRNA I (Mouse Specific) (+), using PLCγ1 (D9H10) XP ® Rabbit mAb #5690 (upper) or α-Tubulin (11H10) Rabbit mAb #2125 (lower). The PLCγ1 (D9H10) XP ® Rabbit mAb confirms silencing of PLCγ1 expression, while the α-Tubulin (11H10) Rabbit mAb is used as a loading control.

PLC γ1 CRISPR/Cas9 KO Plasmid (m) - sc-422299 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 HDR Plasmid (m) - sc-422299-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 Double Nickase Plasmid (m) - sc-422299-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 Double Nickase Plasmid (m2) - sc-422299-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 CRISPR Activation Plasmid (m) - sc-422299-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 CRISPR Activation Plasmid (m2) - sc-422299-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 Lentiviral Activation Particles (m) - sc-422299-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 Lentiviral Activation Particles (m2) - sc-422299-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

PLC γ1 siRNA (m) - sc-36265 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

PLC γ1 shRNA Plasmid (m) - sc-36265-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

PLC γ1 shRNA (m) Lentiviral Particles - sc-36265-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU071491 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN38857 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38857 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PLCG1 siRNA (Mouse) - CRM3118 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse Plcg1 (NM_021280.3) - SHH377222 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Plcg1(NM_021280.3) - SHR120156 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse PLCG1 siRNA - orb282594 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

PLCG1 shRNA Plasmid (Mouse) - CHM3118 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

PLCG1 miRNA 3'UTR clone - MiUTR1M-09305 from Creative biogene

Species Reactivities Mouse
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