Gene Symbol | SLC26A7 |
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Entrez Gene | 115111 |
Alt Symbol | SUT2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 26 (anion exchanger), member 7 |
Other Description | anion exchange transporter|solute carrier family 26, member 7|sulfate anion transporter |
Swissprots | Q8TE53 Q96RN2 Q24JS8 Q8TE54 |
Accessions | CAF06391 EAW91679 EAW91680 Q8TE54 AF331521 AAK95665 AI758950 AJ413228 CAC88370 AJ413229 CAC88371 AJ413230 CAC88372 AK122933 AW235609 BC113866 AAI13867 BC114474 AAI14475 NM_001282356 NP_001269285 NM_001282357 NP_001269286 NM_052832 NP_439897 NM_134266 NP_599028 |
Function | Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment-specific anion exchanger. Plays a major role in gastric acid secretion. {ECO:0000250|UniProtKB:Q8R2Z3, ECO:0000269|PubMed:11834742, ECO:0000269|PubMed:12736153}. |
Subcellular Location | Recycling endosome membrane {ECO:0000269|PubMed:16524946}; Multi-pass membrane protein {ECO:0000269|PubMed:16524946}. Note=Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion. {ECO:0000269|PubMed:16524946}. |
Tissue Specificity | Expressed in tonsillar high endothelial venule endothelial cells (HEVEC), placenta and in testis, expressed in a subgroup of basal cells in the epididymal ducts. {ECO:0000269|PubMed:11829495, ECO:0000269|PubMed:11834742, ECO:0000269|PubMed:15956810, ECO:0000269|PubMed:17504921}. |
Top Pathways | Gastric acid secretion |
SLC26A7 (14H5) - sc-53960 from Santa Cruz Biotechnology
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SLC26A7 (N-14) - sc-98134 from Santa Cruz Biotechnology
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SLC26A7 (T-16) - sc-98135 from Santa Cruz Biotechnology
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Anti-SLC26A7 Antibody (C-Terminus, clone 14H5, Biotin) - LS-C141705 from LifeSpan Bioscience
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Anti-SLC26A7 Antibody (C-Terminus, clone 14H5, DY488) - LS-C141707 from LifeSpan Bioscience
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Anti-SLC26A7 Antibody (C-Terminus, clone 14H5, DY650) - LS-C141706 from LifeSpan Bioscience
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Anti-SLC26A7 Antibody (C-Terminus, clone 14H5, HRP) - LS-C141708 from LifeSpan Bioscience
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Anti-SLC26A7 Antibody (C-Terminus, clone 14H5) - LS-C49175 from LifeSpan Bioscience
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Anti-SLC26A7 Antibody (C-Terminus, clone 14H5, DY550) - LS-C141709 from LifeSpan Bioscience
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Anti-SLC26A7 Antibody - LS-C179273 from LifeSpan Bioscience
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SLC26A7 antibody - 17654-1-AP from Proteintech Group
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SLC26A7 antibody (14H5) [HRP] - mab50496 from Covalab
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SLC26A7 antibody (14H5) [DyLight 650] - mab50494 from Covalab
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SLC26A7 antibody (14H5) [DyLight 550] - mab50497 from Covalab
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SLC26A7 antibody (14H5) [DyLight 488] - mab50495 from Covalab
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SLC26A7 antibody (14H5) [Biotin] - mab50493 from Covalab
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SLC26A7 Antibody - C-terminal region (ARP10106_P050) - ARP10106_P050 from Aviva Systems Biology
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Anti-SLC26A7 (SUT2) (Human) pAb A08137 - A08137 from Boster Bio
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SLC26A7 antibody - C - terminal region (OAAB09374) - OAAB09374 from Aviva Systems Biology
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