Gene Symbol | EQTN |
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Entrez Gene | 54586 |
Alt Symbol | AFAF, C9orf11, SPACA8, equatorin |
Species | Human |
Gene Type | protein-coding |
Description | equatorin, sperm acrosome associated |
Other Description | acrosome formation associated factor|acrosome formation-associated factor|equatorin|sperm acrosome associated 8 |
Swissprots | B2RPB3 Q96L22 Q9NQ60 Q5TCU1 B7ZMK1 |
Accessions | CAI93406 EAW58566 EAW58567 EAW58568 Q9NQ60 AJ278482 CAC00687 BC014307 AAH14307 BC137351 AAI37352 BC137352 AAI37353 BC144602 AAI44603 BX089774 XM_005251488 XP_005251545 XM_011517920 XP_011516222 NM_001161585 NP_001155057 NM_020641 NP_065692 |
Function | Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. {ECO:0000250}. |
Tissue Specificity | Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood. {ECO:0000269|PubMed:11118625}. |
Anti-AFAF antibody - ab121461 from Abcam
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Anti-AFAF antibody - ab121470 from Abcam
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C9orf11 Antibody - NBP1-90868 from Novus Biologicals
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C9orf11 Antibody - NBP1-90869 from Novus Biologicals
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Anti-EQTN antibody produced in rabbit - HPA015504 from Sigma-Aldrich
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Anti-EQTN antibody produced in rabbit - HPA015089 from Sigma-Aldrich
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C9orf11 antibody - 23168-1-AP from Acris Antibodies
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C9orf11 antibody - 23168-1-AP from Proteintech Group
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C9orf11, Polyclonal Antibody - MBS2517418 from MyBioSource
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C9orf11 Antibody - EPP11044 from Elabscience
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Anti-EQTN (aa 215-294) polyclonal antibody - DPABH-17977 from Creative Diagnostics
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Anti-EQTN (aa 35-182) polyclonal antibody - DPABH-18041 from Creative Diagnostics
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Afaf (S-14) - sc-163655 from Santa Cruz Biotechnology
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Anti-C9orf11 Antibody - ABN1371 from EMD Millipore
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C9orf11, Polyclonal Antibody - MBS767374 from MyBioSource
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anti-C9orf11 antibody - A001142 from Biobool
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Anti-C9ORF11 polyclonal antibody - CABT-BL804 from Creative Diagnostics
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C9orf11 antibody - N - terminal region (OAAB12022) - OAAB12022 from Aviva Systems Biology
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Anti-Equatorin / AFAF Antibody - LS-C661647 from LifeSpan Bioscience
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