| Gene Symbol |
EQTN
|
| Entrez Gene |
54586
|
| Alt Symbol |
AFAF, C9orf11, SPACA8, equatorin
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
equatorin, sperm acrosome associated
|
| Other Description |
acrosome formation associated factor|acrosome formation-associated factor|equatorin|sperm acrosome associated 8
|
| Swissprots |
B2RPB3 Q96L22 Q9NQ60 Q5TCU1 B7ZMK1
|
| Accessions |
CAI93406 EAW58566 EAW58567 EAW58568 Q9NQ60 AJ278482 CAC00687 BC014307 AAH14307 BC137351 AAI37352 BC137352 AAI37353 BC144602 AAI44603 BX089774 XM_005251488 XP_005251545 XM_011517920 XP_011516222 NM_001161585 NP_001155057 NM_020641 NP_065692
|
| Function |
Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. {ECO:0000250}.
|
| Tissue Specificity |
Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood. {ECO:0000269|PubMed:11118625}.
|
