Gene Symbol | EQTN |
---|---|
Entrez Gene | 54586 |
Alt Symbol | AFAF, C9orf11, SPACA8, equatorin |
Species | Human |
Gene Type | protein-coding |
Description | equatorin, sperm acrosome associated |
Other Description | acrosome formation associated factor|acrosome formation-associated factor|equatorin|sperm acrosome associated 8 |
Swissprots | B2RPB3 Q96L22 Q9NQ60 Q5TCU1 B7ZMK1 |
Accessions | CAI93406 EAW58566 EAW58567 EAW58568 Q9NQ60 AJ278482 CAC00687 BC014307 AAH14307 BC137351 AAI37352 BC137352 AAI37353 BC144602 AAI44603 BX089774 XM_005251488 XP_005251545 XM_011517920 XP_011516222 NM_001161585 NP_001155057 NM_020641 NP_065692 |
Function | Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis. {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. {ECO:0000250}. |
Tissue Specificity | Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood. {ECO:0000269|PubMed:11118625}. |
Afaf CRISPR/Cas9 KO Plasmid (h) - sc-412311 from Santa Cruz Biotechnology
|
||||||||
Afaf HDR Plasmid (h) - sc-412311-HDR from Santa Cruz Biotechnology
|
||||||||
Afaf Double Nickase Plasmid (h) - sc-412311-NIC from Santa Cruz Biotechnology
|
||||||||
Afaf Double Nickase Plasmid (h2) - sc-412311-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Afaf CRISPR Activation Plasmid (h) - sc-412311-ACT from Santa Cruz Biotechnology
|
||||||||
Afaf CRISPR Activation Plasmid (h2) - sc-412311-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Afaf Lentiviral Activation Particles (h) - sc-412311-LAC from Santa Cruz Biotechnology
|
||||||||
Afaf Lentiviral Activation Particles (h2) - sc-412311-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Afaf siRNA (h) - sc-92976 from Santa Cruz Biotechnology
|
||||||||
Afaf shRNA Plasmid (h) - sc-92976-SH from Santa Cruz Biotechnology
|
||||||||
Afaf shRNA (h) Lentiviral Particles - sc-92976-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU009641 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5167 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5167 from Sigma-Aldrich
|
||||||||
EQTN siRNA (Human) - CRJ0148 from Cohesion Biosciences
|
||||||||
EQTN - MBS8213130 from MyBioSource
|
||||||||
shRNA set against Human C9orf11 (NM_020641.2) - SHH252789 from Creative biogene
|
||||||||
Human EQTN siRNA - orb270649 from Biorbyt
|
||||||||
EQTN shRNA Plasmid (Human) - CHJ0148 from Cohesion Biosciences
|
||||||||
EQTN miRNA 3'UTR clone - MiUTR4H-TG01194 from Creative biogene
|