SLC6A3

Gene Symbol SLC6A3
Entrez Gene 6531
Alt Symbol DAT, DAT1, PKDYS
Species Human
Gene Type protein-coding
Description solute carrier family 6 (neurotransmitter transporter), member 3
Other Description DA transporter|dopamine transporter 1|sodium-dependent dopamine transporter|solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Swissprots A2RUN4 Q14996 Q01959
Accessions AAC50179 AAC51876 AAD26197 AAG33844 AAT38106 BAA22511 CAA71229 CAJ46923 CBX36861 CBY79733 CBY79752 CBY79771 CBY88727 CBY88755 CBY88774 CCA61663 CCA61682 CCA61701 CCA64028 CCA64149 CCA64168 CCA65378 CCA65409 CCD32738 EAX08158 EAX08159 EAX08160 Q01959 AI586989 AK310589 BC132977 AAI32978 BC133003 AAI33004 EF174603 ABO77644 L24178 AAA19560 M95167 AAC41720 M96670 AAA35770 S44626 AAB23443 S46955 AAA11754 NM_001044 NP_001035
Function Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. {ECO:0000269|PubMed:15505207}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:15505207}; Multi-pass membrane protein {ECO:0000269|PubMed:15505207}.
Tissue Specificity Highly expressed in substantia nigra. {ECO:0000269|PubMed:7637582}.
Top Pathways Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism

DAT (6-8D6) - sc-32259 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
DAT (6-8D6): sc-32259. Immunoperoxidase staining of paraformaldehyde fixed, frozen sections of normal mouse brain tissue showing striatum (A) and Substantia nigra (B) staining. Kindly provided by Dr. Allan Levey and Dr. Howard Rees at Emory University.

DAT (6-5G10) - sc-32258 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
DAT (6-5G10): sc-32258. Immunoperoxidase staining of paraformaldehyde fixed, frozen sections of normal mouse brain tissue showing striatum (A) andSubstantia nigra (B) staining. Kindly provided by Dr. Allan Levey and Dr. Howard Rees at Emory University.

DAT (C-20) - sc-1433 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAT (C-20): sc-1433. Western blot analysis of human recombinant DAT fusion protein.

DAT (H-80) - sc-14002 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DAT (H-80): sc-14002. Western blot analysis of DAT expression in K-562 (A) and HEK293 (B) whole cell lysates.

DAT (hDAT-LOOP) - sc-58517 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
DAT (hDAT-LOOP): sc-58517. Immunoperoxidase staining of formalin fixed, paraffin-embedded human hippocampus tissue showing cytoplasmic staining of neuronal cells and glial cells.

DAT (K-20) - sc-7514 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAT (K-20): sc-7514. Western blot analysis of human recombinant DAT fusion protein.

DAT (N-19) - sc-7515 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DAT (N-19): sc-7515. Western blot analysis of DAT expression in HeLa (A) and HEK293 (B) whole cell lysates.

Anti-Dopamine Transporter antibody - ab5990 from Abcam

Prices $378.00
Sizes 50 µg
Host Rat
Clonality Monoclonal

Anti-Dopamine Transporter antibody - ab111468 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Dopamine Transporter antibody (ab111468) at 1 µg/mlLane 1 : Mouse Olfactory Bulb LysateLane 2 : Forebrain (Mouse) Tissue LysateLane 3 : Rat Forebrain Rat Tissue LysateLane 4 : Rat Cortex Tissue Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Dopamine Transporter antibody - ab18548 from Abcam

Prices $370.00
Sizes 25 µl
Host Rabbit
Clonality Polyclonal

Anti-Dopamine Transporter antibody - ab27950 from Abcam

Prices $372.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Dopamine Transporter antibody - ab78068 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Formalin/PFA-fixed ,paraffin-embedded human cerebellum tissue labelled with ab76068 at 20 µg/ml.

Anti-Dopamine Transporter antibody - ab130140 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-Dopamine Transporter antibody (ab130140) at 1 µg/ml + Human Substantia nigra lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Dopamine Transporter antibody - ab78534 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Dopamine Transporter antibody [EPR7863] - ab133693 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7863
Flow cytometric analysis of K562 cells labelling Dopamine Transporter with ab133693 (red) or a rabbit IgG (negative) (green).

Anti-Dopamine Transporter antibody [hDAT-LOOP] - ab5981 from Abcam

Prices $387.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone hDAT-LOOP

Anti-SLC6A3 / Dopamine Transporter Antibody (N-Terminus, clone 4F8) - LS-C11197 from LifeSpan Bioscience

Prices $550.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
Clone 4F8

Anti-SLC6A3 / Dopamine Transporter Antibody (N-Terminus) - LS-C22942 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µl
Host Rat
Clonality Monoclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (N-Terminus) - LS-C22946 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (N-Terminus) - LS-C22945 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (C-Terminus) - LS-C22947 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (C-Terminus) - LS-C22948 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (N-Terminus) - LS-C22950 from LifeSpan Bioscience

Prices $485.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (AP) - LS-C87001 from LifeSpan Bioscience

Prices $695.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC6A3 / Dopamine Transporter Antibody (N-Terminus) - LS-C123419 from LifeSpan Bioscience

Prices $725.00
Sizes 100 µl
Host Rat
Clonality Monoclonal
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