| Gene Symbol |
SLC6A3
|
| Entrez Gene |
6531
|
| Alt Symbol |
DAT, DAT1, PKDYS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 6 (neurotransmitter transporter), member 3
|
| Other Description |
DA transporter|dopamine transporter 1|sodium-dependent dopamine transporter|solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
|
| Swissprots |
A2RUN4 Q14996 Q01959
|
| Accessions |
AAC50179 AAC51876 AAD26197 AAG33844 AAT38106 BAA22511 CAA71229 CAJ46923 CBX36861 CBY79733 CBY79752 CBY79771 CBY88727 CBY88755 CBY88774 CCA61663 CCA61682 CCA61701 CCA64028 CCA64149 CCA64168 CCA65378 CCA65409 CCD32738 EAX08158 EAX08159 EAX08160 Q01959 AI586989 AK310589 BC132977 AAI32978 BC133003 AAI33004 EF174603 ABO77644 L24178 AAA19560 M95167 AAC41720 M96670 AAA35770 S44626 AAB23443 S46955 AAA11754 NM_001044 NP_001035
|
| Function |
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. {ECO:0000269|PubMed:15505207}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:15505207}; Multi-pass membrane protein {ECO:0000269|PubMed:15505207}.
|
| Tissue Specificity |
Highly expressed in substantia nigra. {ECO:0000269|PubMed:7637582}.
|
| Top Pathways |
Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism
|