Gene Symbol | SLC6A3 |
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Entrez Gene | 6531 |
Alt Symbol | DAT, DAT1, PKDYS |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 6 (neurotransmitter transporter), member 3 |
Other Description | DA transporter|dopamine transporter 1|sodium-dependent dopamine transporter|solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 |
Swissprots | A2RUN4 Q14996 Q01959 |
Accessions | AAC50179 AAC51876 AAD26197 AAG33844 AAT38106 BAA22511 CAA71229 CAJ46923 CBX36861 CBY79733 CBY79752 CBY79771 CBY88727 CBY88755 CBY88774 CCA61663 CCA61682 CCA61701 CCA64028 CCA64149 CCA64168 CCA65378 CCA65409 CCD32738 EAX08158 EAX08159 EAX08160 Q01959 AI586989 AK310589 BC132977 AAI32978 BC133003 AAI33004 EF174603 ABO77644 L24178 AAA19560 M95167 AAC41720 M96670 AAA35770 S44626 AAB23443 S46955 AAA11754 NM_001044 NP_001035 |
Function | Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. {ECO:0000269|PubMed:15505207}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15505207}; Multi-pass membrane protein {ECO:0000269|PubMed:15505207}. |
Tissue Specificity | Highly expressed in substantia nigra. {ECO:0000269|PubMed:7637582}. |
Top Pathways | Dopaminergic synapse, Amphetamine addiction, Cocaine addiction, Alcoholism |
Human Dopamine Transporter full length protein - ab152684 from Abcam
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Human Dopamine Transporter protein fragment - ab112352 from Abcam
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DAT1 / LMO3 Antibody Blocking Peptide - LS-E13689 from LifeSpan Bioscience
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SLC6A3 / Dopamine Transporter Antibody Blocking Peptide - LS-E27827 from LifeSpan Bioscience
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SLC6A3 / Dopamine Transporter Antibody Blocking Peptide - LS-E16100 from LifeSpan Bioscience
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Recombinant Human SLC6A3/DAT1 Protein - H00006531-Q01 from Novus Biologicals
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Recombinant Human SLC6A3/DAT1 Protein - H00006531-P01 from Novus Biologicals
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SLC6A3-Antibody-C-term-Blocking-Peptide - BP16940b from Abgent, a WuXi AppTec company
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SLC6A3 Blocking Peptide - 33R-3700 from Fitzgerald
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Dopamine Transporter Peptide - AC21-2637-P from Abcore
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SLC6A3 / DAT - H00006531-P01 from Acris Antibodies
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SLC6A3 / DAT - H00006531-Q01-10 from Acris Antibodies
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SLC6A3 / DAT - H00006531-Q01-25 from Acris Antibodies
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SLC6A3 Peptide - 42-964P from ProSci
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SLC6A3 fusion protein - Ag18297 from Proteintech Group
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Recombinant Human SLC6A3 - SLC6A3-26889TH from Creative Biomart
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Recombinant Human SLC6A3, GST-tagged - SLC6A3-2782H from Creative Biomart
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Recombinant Dopamine Transporter (DAT) - RPB625Hu01 from Uscn Life Science Inc.
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Recombinant Dopamine Transporter (DAT) - RPB625Ra01 from Uscn Life Science Inc.
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Recombinant Dopamine Transporter (DAT) - RPB625Hu01 from Cloud-clone
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SLC6A3/DAT, Peptide - MBS427394 from MyBioSource
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SLC6A3/DAT1 Recombinant Protein Antigen - NBP1-91846PEP from Novus Biologicals
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SLC6A3 Recombinant Protein (OPCD02661) - OPCD02661 from Aviva Systems Biology
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SLC6A3 Immunizing peptide - orb66301 from Biorbyt
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