MED12

Gene Symbol	MED12
Entrez Gene	9968
Alt Symbol	ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230
Species	Human
Gene Type	protein-coding
Description	mediator complex subunit 12
Other Description	CAG repeat protein 45|OPA-containing protein|activator-recruited cofactor 240 kDa component|human opposite paired|mediator of RNA polymerase II transcription subunit 12|mediator of RNA polymerase II transcription, subunit 12 homolog|putative mediator subunit 12|thyroid hormone receptor-associated protein complex 230 kDa component|thyroid hormone receptor-associated protein, 230 kDa subunit|trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit)|trinucleotide repeat-containing gene 11 protein
Swissprots	Q93074 Q9UND7 Q9UHV6 O75557 O15410
Accessions	AAD44162 BAC81020 BAC81021 BAC81022 BAC81023 BAC81024 BAC81025 BAC81026 BAC81027 BAC81028 BAC81029 BAC81030 BAC81031 BAC81032 BAC81033 BAC81034 BAC81035 BAC81036 BAC81037 BAC81038 BAC81039 BAC81050 BAC81051 BAC81052 BAC81053 BAC81054 BAC81055 BAC81056 BAC81057 BAC81058 BAC81059 BAC81060 BAC81061 BAC81062 BAC81063 BAC81064 BAC81065 BAC81066 BAC81067 BAC81068 BAC81069 BAC81080 BAC81081 BAC81082 BAC81083 BAC81084 BAC81085 BAC81086 BAC81087 BAC81088 BAC81089 BAC81090 BAC81091 BAC81092 BAC81093 BAC81094 BAC81095 BAC81096 BAC81097 BAC81098 BAC81099 EAX05314 EAX05315 EAX05316 EAX05317 EAX05318 Q93074 AB102668 BAC81137 AF071309 AAC83163 AJ306428 CAC84084 AK302543 BAG63815 BC127264 BC156136 AAI56137 BC156978 AAI56979 BM662470 D83783 BAA12112 DB069668 FN430679 CAZ90628 U23863 U80742 AAB91440 XM_005262317 XP_005262374 XM_005262319 XP_005262376 NM_005120 NP_005111
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. {ECO:0000269|PubMed:16565090, ECO:0000269|PubMed:16595664, ECO:0000269|PubMed:17000779}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10198638}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MED12 peptide - ab60803 from Abcam Category Peptide

Human MED12 protein fragment - ab153031 from Abcam Category Protein Source Wheat germ Species Human

MED12 Antibody Blocking Peptide - LS-E27712 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human MED12 Protein - H00009968-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

MED12 Peptide - AC21-2852-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

MED12 - H00009968-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

MED12 - H00009968-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TRAP230 Blocking Peptide - CBP4084 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Recombinant Human Mediator of RNA polymerase II transcription subunit 12(MED12) - CSB-YP853101HU CSB-EP853101HU CSB-BP853101HU CSB-MP853101HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

MED12, Peptide - MBS427848 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

TRAP230 Blocking Peptide - abx162577 from Abbexa Category Peptide Species Human, Mouse, Rat

MED12 Recombinant Protein Antigen - NBP1-86670PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Source E.coli Species Human

MED12 Recombinant Protein Antigen - NBP1-86669PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MED12 Peptide, Human - M34GP09355H from Creative Peptides Category Peptide Source Synthetic. Species Human

Mediator of RNA polymerase II transcription subunit 12 (MED12), partial, Recombinant Protein - MBS1448623 from MyBioSource Category Protein Prices $1,685.00, $1,840.00, $1,985.00, $2,100.00, $2,295.00, $2,335.00, $2,620.00, $2,895.00, $3,320.00, $4,140.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TRAP230 peptide - orb256971 from Biorbyt Category Peptide

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