Gene Symbol | STRA13 |
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Entrez Gene | 201254 |
Alt Symbol | CENP-X, CENPX, D9, FAAP10, MHF2 |
Species | Human |
Gene Type | protein-coding |
Description | stimulated by retinoic acid 13 |
Other Description | FANCM-interacting histone fold protein 2|Fanconi anemia-associated polypeptide of 10 kDa|centromere protein X|retinoic acid-inducible gene D9 protein homolog|stimulated by retinoic acid 13 homolog|stimulated by retinoic acid gene 13 protein homolog |
Swissprots | O00281 Q96F51 O00282 Q96DD4 A8MT69 |
Accessions | A8MT69 CAI93454 BC009571 AAH09571 BC011610 AAH11610 BI837753 BQ648002 CB110145 DQ893089 ABM84015 DQ896361 ABM87360 HY110543 U95006 AAB53638 U95007 AAB53639 XM_005256339 XP_005256396 NM_001271006 NP_001257935 NM_001271007 NP_001257936 NM_144998 NP_659435 |
Function | DNA-binding component of the FA core complex involved in DNA damage repair and genome maintenance. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. Component of the APITD1/CENPS complex that is essential for the stable assembly of the outer kinetochore. Plays an important role in mitotic progression and chromosome segregation. {ECO:0000269|PubMed:19620631, ECO:0000269|Ref.5, ECO:0000269|Ref.6}. |
Subcellular Location | Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. |
Top Pathways | Fanconi anemia pathway |
MHF2 peptide - ab157687 from Abcam
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STRA13 fusion protein - ag9044 from Proteintech Group
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Recombinant Human STRA13, GST-tagged - STRA13-3019H from Creative Biomart
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Recombinant Pongo abelii Centromere protein X(STRA13) - CSB-YP722403PYX CSB-EP722403PYX CSB-BP722403PYX CSB-MP722403PYX from Cusabio
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Recombinant Human Centromere protein X(STRA13) - CSB-YP022871HU CSB-EP022871HU CSB-BP022871HU CSB-MP022871HU from Cusabio
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STRA13 - TP303240 from Acris Antibodies
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Centromere protein X (STRA13), Recombinant Protein - MBS1011350 from MyBioSource
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