Gene Symbol | CD38 |
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Entrez Gene | 952 |
Alt Symbol | ADPRC 1, T10 |
Species | Human |
Gene Type | protein-coding |
Description | CD38 molecule |
Other Description | 2'-phospho-ADP-ribosyl cyclase|2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase|2'-phospho-cyclic-ADP-ribose transferase|ADP-ribosyl cyclase 1|ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1|CD38 antigen (p45)|NAD(+) nucleosidase|cADPr hydrolase 1|cyclic ADP-ribose hydrolase 1 |
Swissprots | P28907 Q96HY4 O00122 O00121 |
Accessions | AAY99634 BAA18966 CDM22270 EAW92745 EAW92746 P28907 AA417096 AK297592 BAG59979 AK303169 BAG64268 AK313268 BAG36077 BC007964 AAH07964 CD688069 D84276 BAA18964 D84277 BAA18965 DQ893184 ABM84110 EU176777 ABW03578 M34461 AAA68482 XR_241678 NM_001775 NP_001766 |
Function | Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. {ECO:0000269|PubMed:9074508}. |
Top Pathways | Hematopoietic cell lineage, Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Epstein-Barr virus infection |
CD38 Antibody - 14637 from Cell Signaling Technology
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CD38 (H-11) - sc-374650 from Santa Cruz Biotechnology
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CD38 (HB-7) - sc-18858 from Santa Cruz Biotechnology
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CD38 (N-17) - sc-7048 from Santa Cruz Biotechnology
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CD38 (H-170) - sc-15362 from Santa Cruz Biotechnology
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CD38 (AT1) - sc-7325 from Santa Cruz Biotechnology
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CD38 (C-19) - sc-7047 from Santa Cruz Biotechnology
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CD38 (AT13/5) - sc-59028 from Santa Cruz Biotechnology
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CD38 (T16) - sc-51726 from Santa Cruz Biotechnology
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Anti-CD38 antibody - ab125038 from Abcam
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Anti-CD38 antibody - ab140799 from Abcam
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Anti-CD38 antibody - ab108155 from Abcam
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Anti-CD38 antibody [38C03], prediluted - ab75231 from Abcam
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Anti-CD38 antibody [6E12D] - ab93941 from Abcam
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Anti-CD38 antibody [AT13/5] - ab9504 from Abcam
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Anti-CD38 antibody [AT13/5] (FITC) - ab30419 from Abcam
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Anti-CD38 antibody [B307 (AT1)] - ab131420 from Abcam
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Anti-CD38 antibody [EPR4106] - ab108403 from Abcam
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Anti-CD38 antibody [FS02] - ab1260 from Abcam
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Anti-CD38 antibody [FS02] (FITC) - ab1173 from Abcam
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Anti-CD38 antibody [FS02] (Phycoerythrin) - ab1174 from Abcam
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Anti-CD38 antibody [GR7A4] - ab91390 from Abcam
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Anti-CD38 antibody [GR7A4] (Allophycocyanin) - ab90946 from Abcam
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Anti-CD38 antibody [GR7A4] (CF405M) - ab117772 from Abcam
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Anti-CD38 antibody [GR7A4] (FITC) - ab90877 from Abcam
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