CLEC5A

Gene Symbol CLEC5A
Entrez Gene 23601
Alt Symbol CLECSF5, MDL-1, MDL1
Species Human
Gene Type protein-coding
Description C-type lectin domain family 5, member A
Other Description C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5|C-type lectin domain family 5 member A|C-type lectin superfamily member 5|myeloid DAP12-associating lectin 1|myeloid DAP12-associating lectin-1
Swissprots Q9UKQ0 Q52M11 Q9NY25
Accessions AAS07444 EAL24012 EAW83991 EAW83992 Q9NY25 AF139768 AAF02491 AI418484 AJ271684 CAB71334 AK292766 BAF85455 AK295200 BAG58199 AK307095 AK313703 BAG36449 BC093714 AAH93714 BC112099 AAI12100 BC113098 AAI13099 BC113099 AAI13100 BC143392 BQ005467 BQ446122 XM_011515995 XP_011514297 XR_927428 NM_001301167 NP_001288096 NM_013252 NP_037384
Function Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation (By similarity). Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release. {ECO:0000250, ECO:0000269|PubMed:10449773, ECO:0000269|PubMed:18496526}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:21566123}; Single-pass type II membrane protein {ECO:0000269|PubMed:21566123}.
Tissue Specificity Expressed in peripheral blood monocytes and in the monocyte/macrophage cell lines U-937 and Mono-Mac-6, but not in cell lines of other origins. Expression is down-regulated when monocytes differentiate into dendritic cells. {ECO:0000269|PubMed:10449773}.

CLEC-5A CRISPR/Cas9 KO Plasmid (h) - sc-406859 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A HDR Plasmid (h) - sc-406859-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A Double Nickase Plasmid (h) - sc-406859-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A Double Nickase Plasmid (h2) - sc-406859-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A CRISPR Activation Plasmid (h) - sc-406859-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A CRISPR Activation Plasmid (h2) - sc-406859-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A Lentiviral Activation Particles (h) - sc-406859-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A Lentiviral Activation Particles (h2) - sc-406859-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-5A siRNA (h) - sc-89348 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLEC-5A shRNA Plasmid (h) - sc-89348-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLEC-5A shRNA (h) Lentiviral Particles - sc-89348-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU143101 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6222 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6222 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLEC5A siRNA (Human) - CRH8390 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLEC5A - MBS8204288 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLEC5A(NM_013252.2) - SHG182233 from Creative biogene

Category siRNA
Species Reactivities Human

CLEC5A shRNA Plasmid (Human) - CHH8390 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLEC5A miRNA 3'UTR clone - MiUTR1H-02214 from Creative biogene

Species Reactivities Human
Search more