Gene Symbol | GABRA1 |
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Entrez Gene | 2554 |
Alt Symbol | ECA4, EIEE19, EJM, EJM5 |
Species | Human |
Gene Type | protein-coding |
Description | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
Other Description | GABA(A) receptor subunit alpha-1|GABA(A) receptor, alpha 1|gamma-aminobutyric acid receptor subunit alpha-1 |
Swissprots | D3DQK6 P14867 Q8N629 |
Accessions | EAW61537 EAW61538 EAW61539 P14867 AK223447 BAD97167 AK289792 BAF82481 AK295160 BAG58174 AV720972 AW148652 BC030696 AAH30696 BM927274 DA075784 DA228536 DA232066 DB485936 DB487114 DC307259 DC325179 DC334834 DQ890915 ABM81841 R60404 X13584 CAA31925 X14766 CAA32874 NM_000806 NP_000797 NM_001127643 NP_001121115 NM_001127644 NP_001121116 NM_001127645 NP_001121117 NM_001127648 NP_001121120 NM_001127646 NM_001127647 |
Function | Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel (By similarity). {ECO:0000250}. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction |
Human GABA A Receptor alpha 1 full length protein - ab131966 from Abcam
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Human GABA A Receptor alpha 1 peptide - ab95422 from Abcam
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GABRA1 Antibody Blocking Peptide - LS-E12461 from LifeSpan Bioscience
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GABRA1 Antibody Blocking Peptide - LS-E12460 from LifeSpan Bioscience
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Recombinant Human GABA-A R alpha 1 Protein - H00002554-P01 from Novus Biologicals
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GABRA1 Blocking Peptide - 33R-10072 from Fitzgerald
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GABRA1 Blocking Peptide - 33R-9935 from Fitzgerald
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GABRA1 Blocking Peptide - abx062119 from Abbexa
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GABRA1 - H00002554-P01-10 from Acris Antibodies
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GABRA1 - H00002554-P01-25 from Acris Antibodies
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GABRA1 fusion protein - Ag3117 from Proteintech Group
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Recombinant Human GABRA1, GST-tagged - GABRA1-13092H from Creative Biomart
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GABRA1 Blocking Peptide - CBP3225 from Cohesion Biosciences
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GABAA Rα1 (L361) Peptide - BS3563P from Bioworld Technology
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GABRA1 Protein - abx165014 from Abbexa
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GABA-A R alpha 1 Protein - NBP2-33762PEP from Novus Biologicals
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GABRA1-Blocking-Peptide-C-term - BP21477b from Abgent, a WuXi AppTec company
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GABRA1 Peptide, Human - M34GP06015H from Creative Peptides
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Gamma-aminobutyric acid receptor subunit alpha-1 (GABRA1), Recombinant Protein - MBS948971 from MyBioSource
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Recombinant Human Gamma-aminobutyric Acid Receptor, alpha-1 - 230-00874-10 from RayBiotech
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GABRA1 peptide - orb72707 from Biorbyt
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GABRA1 peptide - orb219088 from Biorbyt
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Recombinant Human GABRA1 Protein, GST-tagged - GABRA1-4635H from Creative Biomart
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