GABRA1

Gene Symbol GABRA1
Entrez Gene 2554
Alt Symbol ECA4, EIEE19, EJM, EJM5
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, alpha 1
Other Description GABA(A) receptor subunit alpha-1|GABA(A) receptor, alpha 1|gamma-aminobutyric acid receptor subunit alpha-1
Swissprots D3DQK6 P14867 Q8N629
Accessions EAW61537 EAW61538 EAW61539 P14867 AK223447 BAD97167 AK289792 BAF82481 AK295160 BAG58174 AV720972 AW148652 BC030696 AAH30696 BM927274 DA075784 DA228536 DA232066 DB485936 DB487114 DC307259 DC325179 DC334834 DQ890915 ABM81841 R60404 X13584 CAA31925 X14766 CAA32874 NM_000806 NP_000797 NM_001127643 NP_001121115 NM_001127644 NP_001121116 NM_001127645 NP_001121117 NM_001127648 NP_001121120 NM_001127646 NM_001127647
Function Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel (By similarity). {ECO:0000250}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction

GABA A Rα1 CRISPR/Cas9 KO Plasmid (h) - sc-401038 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 HDR Plasmid (h) - sc-401038-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 Double Nickase Plasmid (h) - sc-401038-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 Double Nickase Plasmid (h2) - sc-401038-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 CRISPR Activation Plasmid (h) - sc-401038-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 CRISPR Activation Plasmid (h2) - sc-401038-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 Lentiviral Activation Particles (h) - sc-401038-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 Lentiviral Activation Particles (h2) - sc-401038-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

GABA A Rα1 siRNA (h) - sc-42425 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABA A Rα1 shRNA Plasmid (h) - sc-42425-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABA A Rα1 shRNA (h) Lentiviral Particles - sc-42425-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

GABA-A R alpha 1 RNAi - H00002554-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU133951 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1818 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1818 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10978 from Sigma-Aldrich

Category miRNA

GABRA1 siRNA (Human) - CRH1692 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABRA1 - MBS8222233 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GABRA1 (NM_000806.5) - SHH298437 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human GABRA1(NM_000806.5) - SHH073633 from Creative biogene

Category siRNA
Species Reactivities Human

Human GABRA1 siRNA - orb262194 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GABRA1 shRNA Plasmid (Human) - CHH1692 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GABRA1 miRNA 3'UTR clone - MiUTR1H-03909 from Creative biogene

Species Reactivities Human
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