Gene Symbol |
CCR7
|
Entrez Gene |
1236
|
Alt Symbol |
BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chemokine (C-C motif) receptor 7
|
Other Description |
Bukitt's lymphoma receptor 2|C-C chemokine receptor type 7|CC chemokine receptor 7|EBV-induced G protein-coupled receptor 1|Epstein-Barr virus induced gene 1|Epstein-Barr virus-induced G-protein coupled receptor 1|MIP-3 beta receptor|lymphocyte-specific G protein-coupled peptide receptor
|
Swissprots |
P32248
|
Accessions |
AAA74230 ABK41941 CAY55956 EAW60669 P32248 AK127810 BAG54575 AK310277 AK312732 BAG35603 AY587876 AAT52232 BC035343 AAH35343 BI910219 BU740631 DA814913 DQ892114 ABM83040 DQ895308 ABM86234 HY017993 HY021417 L08176 AAA58615 L31581 AAA74231 NM_001301714 NP_001288643 NM_001301716 NP_001288645 NM_001301717 NP_001288646 NM_001301718 NP_001288647 NM_001838 NP_001829
|
Function |
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
|
Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
|
Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Transcriptional misregulation in cancer
|