Gene Symbol | CCR7 |
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Entrez Gene | 1236 |
Alt Symbol | BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 7 |
Other Description | Bukitt's lymphoma receptor 2|C-C chemokine receptor type 7|CC chemokine receptor 7|EBV-induced G protein-coupled receptor 1|Epstein-Barr virus induced gene 1|Epstein-Barr virus-induced G-protein coupled receptor 1|MIP-3 beta receptor|lymphocyte-specific G protein-coupled peptide receptor |
Swissprots | P32248 |
Accessions | AAA74230 ABK41941 CAY55956 EAW60669 P32248 AK127810 BAG54575 AK310277 AK312732 BAG35603 AY587876 AAT52232 BC035343 AAH35343 BI910219 BU740631 DA814913 DQ892114 ABM83040 DQ895308 ABM86234 HY017993 HY021417 L08176 AAA58615 L31581 AAA74231 NM_001301714 NP_001288643 NM_001301716 NP_001288645 NM_001301717 NP_001288646 NM_001301718 NP_001288647 NM_001838 NP_001829 |
Function | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Transcriptional misregulation in cancer |
CKR-7 CRISPR/Cas9 KO Plasmid (h) - sc-402150 from Santa Cruz Biotechnology
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CKR-7 HDR Plasmid (h) - sc-402150-HDR from Santa Cruz Biotechnology
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CKR-7 Double Nickase Plasmid (h) - sc-402150-NIC from Santa Cruz Biotechnology
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CKR-7 Double Nickase Plasmid (h2) - sc-402150-NIC-2 from Santa Cruz Biotechnology
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CKR-7 CRISPR Activation Plasmid (h) - sc-402150-ACT from Santa Cruz Biotechnology
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CKR-7 CRISPR Activation Plasmid (h2) - sc-402150-ACT-2 from Santa Cruz Biotechnology
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CKR-7 Lentiviral Activation Particles (h) - sc-402150-LAC from Santa Cruz Biotechnology
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CKR-7 Lentiviral Activation Particles (h2) - sc-402150-LAC-2 from Santa Cruz Biotechnology
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CKR-7 siRNA (h) - sc-39888 from Santa Cruz Biotechnology
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CKR-7 shRNA Plasmid (h) - sc-39888-SH from Santa Cruz Biotechnology
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CKR-7 shRNA (h) Lentiviral Particles - sc-39888-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5658 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5658 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07608 from Sigma-Aldrich
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CCR7 siRNA (Human) - CRH0872 from Cohesion Biosciences
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CCR7 - MBS8232091 from MyBioSource
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shRNA set against Human CCR7 (NM_001838.3) - SHH258205 from Creative biogene
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Human CCR7 siRNA - orb261374 from Biorbyt
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CCR7 shRNA Plasmid (Human) - CHH0872 from Cohesion Biosciences
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CCR7 miRNA 3'UTR clone - MiUTR3H-03212 from Creative biogene
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