CCR7

Gene Symbol CCR7
Entrez Gene 1236
Alt Symbol BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
Species Human
Gene Type protein-coding
Description chemokine (C-C motif) receptor 7
Other Description Bukitt's lymphoma receptor 2|C-C chemokine receptor type 7|CC chemokine receptor 7|EBV-induced G protein-coupled receptor 1|Epstein-Barr virus induced gene 1|Epstein-Barr virus-induced G-protein coupled receptor 1|MIP-3 beta receptor|lymphocyte-specific G protein-coupled peptide receptor
Swissprots P32248
Accessions AAA74230 ABK41941 CAY55956 EAW60669 P32248 AK127810 BAG54575 AK310277 AK312732 BAG35603 AY587876 AAT52232 BC035343 AAH35343 BI910219 BU740631 DA814913 DQ892114 ABM83040 DQ895308 ABM86234 HY017993 HY021417 L08176 AAA58615 L31581 AAA74231 NM_001301714 NP_001288643 NM_001301716 NP_001288645 NM_001301717 NP_001288646 NM_001301718 NP_001288647 NM_001838 NP_001829
Function Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7.
Top Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Transcriptional misregulation in cancer

CKR-7 (A-19) - sc-9699 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CKR-7 (A-19): sc-9699. Western blot analysis of CKR-7 expression in K-562 (A), Daudi (B), SP2/0 (C), WEHI-231 (D) and RAW 264.7 (E) whole cell lysates.

CKR-7 (C-18) - sc-9700 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CKR-7 (C-18): sc-9700. Immunofluorescence staining of methanol-fixed Ramos cells showing membrane localization.

CKR-7 (H-60) - sc-25776 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-CCR7 antibody - ab1657 from Abcam

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemical staining for CCR7 in human spleen.

Anti-CCR7 antibody - ab103404 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab103404 stained HeLa cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab103404 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CCR7 antibody - ab191575 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CCR7 antibody (ab191575) at 1 µg/ml + Human spleen tissue lysate at 15 µg

Anti-CCR7 antibody - ab119371 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CCR7 antibody (ab119371) at 1/500 dilutionLane 1 : Jurkat cell lysateLane 2 : Raji cell lysateLane 3 : HeLa cell lysateLane 4 : HEK293 cell lysate

Anti-CCR7 antibody [3D12] - ab95665 from Abcam

Prices $372.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 3D12

Anti-CCR7 antibody [3D12] (Biotin) - ab95666 from Abcam

Prices $378.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone 3D12
Flow cytometry staining of normal Human peripheral blood cells with Anti-Human CD45RA FITC and 1.0 µg of Rat IgG2a ? Isotype Control Biotin (left) or 1.0 µg of ab95666 (right) followed by Streptavidin PE. Cells in the lymphocyte gate were used for analysis.

Anti-CCR7 antibody [3D12], prediluted (Allophycocyanin) - ab155382 from Abcam

Prices $189.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone 3D12
Flow Cytometric analysis of normal Human peripheral blood cells labeling CCR7 with anti-Human CD45RA FITC and Rat IgG2a K Isotype Control APC (left) or ab155382 at 0.125µg (right). Cells in the lymphocyte gate were used for analysis.

Anti-CCR7 antibody [MM0067-9L11] - ab89064 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0067-9L11

Anti-CCR7 antibody [Y59] - ab32527 from Abcam

Prices $401.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y59
All lanes : Anti-CCR7 antibody [Y59] (ab32527) at 1/5000 dilutionLane 1 : K562 cell lysateLane 2 : Daudi cell lysate

Anti-CCR7 antibody [Y59] (Alexa Fluor® 488) - ab196459 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y59
ab196459 staining CCR7 in Jurkat cells. The cells were fixed with 4% formaldehyde (10 min), permeabilised in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated with ab196459 at 1/50 dilution (shown in green) overnight at +4°C. Nuclear DNA was labelled in blue with DAPI.Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-CCR7 antibody [Y59] (Alexa Fluor® 647) - ab196640 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y59
ab196640 staining CCR7 in Jurkat cells. The cells were fixed with 4% formaldehyde (10 min), permeabilised in 0.1% Triton X-100 for 5 minutes and then blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated with ab196640 at 1/100 dilution (shown in red) overnight at +4°C. Nuclear DNA was labelled in blue with DAPI.Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-CCR7 antibody [Y59] (HRP) - ab196475 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone Y59
All lanes : Anti-CCR7 antibody [Y59] (HRP) (ab196475) at 1/5000 dilutionLane 1 : K562 (Human erythromyeloblastoid leukemia cell line) Whole Cell LysateLane 2 : Daudi (Human Burkitt's lymphoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.developed using the ECL techniquePerformed under reducing conditions.

Anti-CCR7 Antibody - LS-C78053 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-CCR7 Antibody (CF) - LS-C78054 from LifeSpan Bioscience

Prices $445.00
Sizes 100 tst
Host Rat
Clonality Monoclonal

Anti-CCR7 Antibody (PE) - LS-C78055 from LifeSpan Bioscience

Prices $495.00
Sizes 100 tst
Host Rat
Clonality Monoclonal

Anti-CCR7 Antibody (aa2-22) - LS-C83960 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CCR7 Antibody (clone 3D12, FITC) - LS-C105838 from LifeSpan Bioscience

Prices $235.00, $305.00
Sizes 25 tst, 100 tst
Host Rat
Clonality Monoclonal
Clone 3D12
Staining of normal human peripheral blood cells with APC anti-human CD45RA (HI100) (LS-C107334) and FITC anti-human CCR7 (3D12). Cells in the lymphocyte gate were used for analysis.

Anti-CCR7 Antibody (N-Terminus) - LS-C171678 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCR7 Antibody (N-Terminus, Magnetic beads) - LS-C171679 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCR7 Antibody (N-Terminus, Sepharose) - LS-C171680 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CCR7 Antibody (clone 4B12, APC) - LS-C107051 from LifeSpan Bioscience

Prices $195.00, $305.00, $385.00
Sizes 10 µg, 50 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 4B12
Staining of C57Bl/6 splenocytes with FITC anti-mouse CD4 (GK1.5) (LS-C106029) and 0.5 ug of APC anti-mouse CCR7 (4B12). Cells were stained at 37uC for 0.5 hours and Fc receptor binding was blocked by staining cells with 5 ug/million cells anti-mouse CD16/32 (LS-C107169). Cells in the lymphocyte gate were used for analysis.

Anti-CCR7 Antibody (aa170-219) - LS-C120557 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using CCR7 Antibody. The picture on the right is treated with the synthesized peptide.
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