BCAS3

Gene Symbol BCAS3
Entrez Gene 54828
Alt Symbol GAOB1, MAAB
Species Human
Gene Type protein-coding
Description breast carcinoma amplified sequence 3
Other Description BCAS4/BCAS3 fusion|breast carcinoma amplified sequence 4/3 fusion protein|breast carcinoma-amplified sequence 3|metastasis associated antigen of breast cancer|protein Maab1
Swissprots Q9H9Y9 Q8TDL9 Q17RM0 Q8WY55 Q8NDR8 Q9BVF0 Q8IXI6 Q9NXP4 Q9H957 Q9H6U6 Q8TDM1 Q6KF21
Accessions EAW51410 EAW51411 EAW51412 EAW51413 EAW51414 EAW51415 EAW51416 Q9H6U6 AF260268 AAF70324 AF361219 AAL99632 AJ511332 CAD54076 AJ518105 CAD57723 AJ518836 CAD57724 AK000135 BAA90966 AK022526 BAB14078 AK023054 BAB14380 AK025510 BAB15156 AK125409 AK225757 AK304791 BAG65541 AK314744 BAG37284 AL831895 CAD38568 BC001250 AAH01250 BC013841 BC017390 AAH17390 BC029983 BC033220 BC036280 BC117275 AAI17276 BC143386 AAI43387 BC143387 AAI43388 BX648103 CA444316 DA188234 DA789232 XM_005257472 XP_005257529 XM_005257475 XP_005257532 XM_011524939 XP_011523241 XM_011524940 XP_011523242 XM_011524941 XP_011523243 XM_011524942 XP_011523244 XM_011524943 XP_011523245 XM_011524944 XP_011523246 XM_011524945 XP_011523247 XM_011524946 XP_011523248 XM_011524947 XP_011523249 XM_011524948 XP_011523250 XM_011524949 XP_011523251 XM_011524950 XP_011523252 XM_011524951 XP_011523253 XM_011524952 XP_011523254 XR_934493 NM_001099432 NP_001092902 NM_017679 NP_060149
Function Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. {ECO:0000250|UniProtKB:Q8CCN5, ECO:0000269|PubMed:17505058}.
Subcellular Location Nucleus {ECO:0000269|PubMed:16617102, ECO:0000269|PubMed:17505058}. Cytoplasm {ECO:0000269|PubMed:16617102, ECO:0000269|PubMed:17505058, ECO:0000269|PubMed:18030336}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q8CCN5}. Note=Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells (By similarity). Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner. {ECO:0000250|UniProtKB:Q8CCN5, ECO:0000269|PubMed:17505058}.
Tissue Specificity Expressed in stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leukocyte and mammary epithelial cells. Expressed in undifferentiated ES cells. Expressed in blood islands and nascent blood vessels derived from differentiated ES cells into embryoid bodies (BD). Expressed in endothelial cells. Not detected in brain. Expressed in brain tumors (at protein level). Expressed in brain. Highly expressed in breast cancers and in glioma cell lines. {ECO:0000269|PubMed:12378525, ECO:0000269|PubMed:16617102, ECO:0000269|PubMed:18030336}.

BCAS3 (D-6) - sc-365131 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BCAS3 (D-6): sc-365131. Western blot analysis of BCAS3 expression in MCF7 (A) and K-562 (B) whole cell lysates.

BCAS3 (D-20) - sc-70025 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BCAS3 (H-300) - sc-98360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BCAS3 (H-300): sc-98360. Western blot analysis of BCAS3 expression in MCF7 (A), HeLa (B) and K-562 (C) whole cell lysates.

BCAS3 (C-20) - sc-70024 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BCAS3 antibody - ab106637 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of BCAS3 in Human breast carcinoma tissue with ab106637 at 20 ug/mL.

Anti-BCAS3 antibody - ab71162 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling BCAS3 with ab71162 at 1/200 (1µg/ml). Detection: DAB.

Anti-BCAS3 antibody - ab92534 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab92534 at 1/500 dilution staining Breast carcinoma amplified sequence 3 in Human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.

Anti-BCAS3 antibody [2066C2a] - ab50973 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2066C2a
Anti-BCAS3 antibody [2066C2a] (ab50973) at 1/100 dilution + A2058 whole cell lysate at 50 µgSecondaryanti-mouse IgG at 1/2500 dilutiondeveloped using the ECL technique

Anti-BCAS3 antibody - C-terminal - ab70919 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BCAS3 antibody - C-terminal (ab70919) at 1/50 dilutionLane 1 : Nontransfected 293 cell line lysateLane 2 : 293 cell line lysate transiently transfected with the Breast carcinoma amplified sequence 3 geneLysates/proteins at 2 µg per lane.

Anti-BCAS3 Antibody (N-Terminus) IHC-plus™ - LS-B4633 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-BCAS3 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4633 concentration 5 ug/ml.

Anti-BCAS3 Antibody (C-Terminus) - LS-C74676 from LifeSpan Bioscience

Prices $545.00
Sizes 20 µg
Host Rabbit
Clonality Polyclonal

Anti-BCAS3 Antibody - LS-C74675 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-BCAS3 Antibody (C-Terminus) - LS-C287754 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BCAS3 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-BCAS3 used at a dilution of 1:200 (1 ug/ml).

Anti-BCAS3 Antibody - LS-C346321 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of MCF7 cell using BCAS3 antibody. Blue: DAPI for nuclear staining.

Anti-BCAS3 Antibody (clone 2066C2a) - LS-C184333 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2066C2a
Immunofluorescent staining using BCAS3 antibody. Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-BCAS3 antibody.

Anti-BCAS3 Antibody (C-Terminus) - LS-C286696 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human BCAS3 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-BCAS3 used at a dilution of 1:500.

Anti-BCAS3 Antibody (clone 2066C2a) - LS-C342387 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2066C2a
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-BCAS3 mAb.

Anti-BCAS3 Antibody (aa835-865) - LS-C98155 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from MCF-7 cell line, using BCAS3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Breast carcinoma amplified sequence 3 Antibody - NBP1-77125 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Breast carcinoma amplified sequence 3 Antibody [NBP1-77125] - Rat brain tissue lysate with BCAS3 antibody at (A) 0.5 and (B) 1 ug/ml.

Breast carcinoma amplified sequence 3 Antibody - NB110-40682 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Breast carcinoma amplified sequence 3 Antibody - NBP2-14348 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Breast carcinoma amplified sequence 3 Antibody [NBP2-14348] Staining of human stomach, upper shows moderate nuclear positivity in glandular cells.

BCAS3 Polyclonal Antibody - bs-6605R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BCAS3 antibody produced in rabbit - SAB3500990 from Sigma-Aldrich

Prices $341.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>BCAS3 Antibody: <B>Cat. No. SAB3500990</B>: Western blot analysis of BCAS3 in Rat brain tissue lysate with BCAS3 antibody at (Lane A) 0.5 and (Lane B) 1 μg/mL.

Anti-BCAS3 (C-term) antibody produced in rabbit - SAB1300543 from Sigma-Aldrich

Prices $291.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BCAS3 (C-term) Antibody: <B>Cat. No. SAB1300543</B>: BCAS3 in human testis tissue with Anti-BCAS3 (C-term) Antibody at 40 μg/mL.

Anti-BCAS3 antibody produced in rabbit - SAB2900810 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-BCAS3 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900810</B>: Anti-BCAS3 antibody IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.
Search more