DIAPH2

Gene Symbol DIAPH2
Entrez Gene 1730
Alt Symbol DIA, DIA2, DRF2, POF, POF2
Species Human
Gene Type protein-coding
Description diaphanous-related formin 2
Other Description diaphanous homolog 2|diaphanous-related formin-2|diaphorase-2|protein diaphanous homolog 2
Swissprots Q9UJL2 Q8WX48 A6NG19 O60878 O60879 Q8WX06
Accessions CAJ42758 EAX02791 EAX02792 EAX02793 O60879 AK002029 BAG51003 AK291272 BAF83961 AW276516 BC117414 AAI17415 BC143838 AAI43839 BX363708 DB062196 U69179 Y15908 CAA75869 Y15909 CAA75870 NM_006729 NP_006720 NM_007309 NP_009293
Function Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. {ECO:0000269|PubMed:12577064}.
Subcellular Location Isoform 3: Cytoplasm, cytosol. Early endosome. Note=Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
Tissue Specificity Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.
Top Pathways Regulation of actin cytoskeleton

Diap2 Antibody - 5474 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using Diap2 Antibody.

Dia 2 (B-11) - sc-55539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dia 2 (B-11): sc-55539. Western blot analysis of Dia 2 expression in PCEP-4 (A) and Adenylyl cyclase I-AC transfected HEK293 (B) whole cell lysates.

Dia 2 (H-3) - sc-393489 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dia 2 (H-3): sc-393489. Western blot analysis of Dia 2 expression in MDA-MB-435S (A) and HeLa (B) whole cell lysates.

Dia 2 (C-12) - sc-393499 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dia 2 (C-12): sc-393499. Western blot analysis of Dia 2 expression in MDA-MB-435S (A) and HeLa (B) whole cell lysates.

Dia 2 (H-110) - sc-28776 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Dia 2 (C-7) - sc-55540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dia 2 (C-7): sc-55540. Western blot analysis of Dia 2 expression in PCEP-4 (A) and Adenylyl cyclase I-AC transfected HEK293 (B) whole cell lysates.

Dia 2 (C-15) - sc-10889 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dia 2 (C-15): sc-10889. Western blot analysis of Dia 2 expression in mouse testis extract.

Dia 2 (N-15) - sc-10892 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dia 2 (N-15): sc-10892. Western blot analysis of Dia 2 expression in PCEP-4 (A) and Adenylyl cyclase I-AC transfected HEK293 (B) whole cell lysates and RAW 264.7 nuclear extract (C).

Dia 2 (R-15) - sc-10891 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dia 2 (R-15): sc-10891. Western blot analysis of Dia 2 expression in non-transfected: sc-110760 (A) and mouse Dia 2 transfected: sc-178523 (B) 293 whole cell lysates.

Anti-DIAPH2 antibody - ab201205 from Abcam

Prices $359.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human fetal testis tissue labeling DIAPH2 with ab201205 at 1/100 dilution.

Anti-DIAPH2 antibody - ab119702 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DIAPH2 antibody (ab119702) at 1/500 dilutionLane 1 : Rat PC12 lysateLane 2 : Human A431 lysateLane 3 : Mouse brain tissue lysateLane 4 : Rabbit spleen fibroblast lysate

Anti-DIAPH2 antibody - ab12319 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 antibody - ab102841 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DIAPH2 antibody (ab102841) at 1/100 dilutionLane 1 : 293 cell lysateLane 2 : MDA-MB435 cell lysateLysates/proteins at 35 µg per lane.

Anti-DIAPH2 antibody - ab10562 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 antibody [EPR13158] - ab181165 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13158
All lanes : Anti-DIAPH2 antibody [EPR13158] (ab181165) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : HCT-116 cell lysateLane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-DIAPH2 antibody - C-terminal - ab189598 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-DIAPH2 antibody - C-terminal (ab189598) at 1/1000 dilutionLane 1 : Mouse thymus total cell extractLane 2 : HeLa total cell extract

Anti-DIAPH2 Antibody (aa1085-1101) - LS-C19007 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DIA-2 Antibody - Western Blot. Western blot of Affinity Purified anti-DIA-2 antibody shows detection of a 132-kD band corresponding to DIA-2 in a lysate prepared from human derived HEK293 cells. Approximately 20 ug of lysate was run on a SDS-PAGE and transferred onto nitrocellulose followed by reaction with a 1:500 dilution of anti-DIA-2 antibody. Detection occurred using a 1:5000 dilution of HRP-labeled Goat anti-Rabbit IgG for 1 hour at room temperature. A chemiluminescence system was used for signal detection (Roche) using a 1 min exposure time.

Anti-DIAPH2 Antibody (aa314-540, clone 12K79) - LS-C182835 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 12K79

Anti-DIAPH2 Antibody (aa877-907, AP) - LS-C256111 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 Antibody (aa877-907, APC) - LS-C256112 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 Antibody (C-Terminus) - LS-C151456 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DIA / DIAPH2 antibody Western Blot of Rat Brain.

Anti-DIAPH2 Antibody (aa877-907, Biotin) - LS-C256113 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 Antibody (aa877-907, Azide-free, HRP) - LS-C256114 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 Antibody (aa877-907, PE) - LS-C256116 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DIAPH2 Antibody (aa877-907, FITC) - LS-C256115 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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