DIAPH2

Gene Symbol DIAPH2
Entrez Gene 1730
Alt Symbol DIA, DIA2, DRF2, POF, POF2
Species Human
Gene Type protein-coding
Description diaphanous-related formin 2
Other Description diaphanous homolog 2|diaphanous-related formin-2|diaphorase-2|protein diaphanous homolog 2
Swissprots Q9UJL2 Q8WX48 A6NG19 O60878 O60879 Q8WX06
Accessions CAJ42758 EAX02791 EAX02792 EAX02793 O60879 AK002029 BAG51003 AK291272 BAF83961 AW276516 BC117414 AAI17415 BC143838 AAI43839 BX363708 DB062196 U69179 Y15908 CAA75869 Y15909 CAA75870 NM_006729 NP_006720 NM_007309 NP_009293
Function Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton. {ECO:0000269|PubMed:12577064}.
Subcellular Location Isoform 3: Cytoplasm, cytosol. Early endosome. Note=Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
Tissue Specificity Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.
Top Pathways Regulation of actin cytoskeleton

Dia 2 CRISPR/Cas9 KO Plasmid (h) - sc-403238 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 HDR Plasmid (h) - sc-403238-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 Double Nickase Plasmid (h) - sc-403238-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 Double Nickase Plasmid (h2) - sc-403238-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 CRISPR Activation Plasmid (h) - sc-403238-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 CRISPR Activation Plasmid (h2) - sc-403238-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 Lentiviral Activation Particles (h) - sc-403238-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 Lentiviral Activation Particles (h2) - sc-403238-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 siRNA (h) - sc-35192 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dia 2 shRNA Plasmid (h) - sc-35192-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dia 2 shRNA (h) Lentiviral Particles - sc-35192-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU088571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7231 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7231 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DIAPH2 siRNA (Human) - CRH1199 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DIAPH2 - MBS8204324 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Dia 2 HDR Plasmid (h2) - sc-403238-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dia 2 CRISPR/Cas9 KO Plasmid (h2) - sc-403238-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human DIAPH2 (NM_006729.4) - SHH278037 from Creative biogene

Category siRNA
Species Reactivities Human

DIAPH2 shRNA Plasmid (Human) - CHH1199 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DIAPH2 miRNA 3'UTR clone - MiUTR1H-02822 from Creative biogene

Species Reactivities Human

DIAPH2 miRNA 3'UTR clone - MiUTR3H-02564 from Creative biogene

Species Reactivities Human
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