PDC

Gene Symbol PDC
Entrez Gene 5132
Alt Symbol MEKA, PHD, PhLOP, PhLP
Species Human
Gene Type protein-coding
Description phosducin
Other Description 33 kDa phototransducing protein|G beta gamma binding protein|phosducin-like orphan protein
Swissprots Q9UP23 Q14816 P20941 Q9UP22
Accessions AAA36210 EAW91212 EAW91213 EAW91214 EAW91215 P20941 AF076464 AAD43142 BC093839 AAH93839 BC112134 AAI12135 BC148616 AAI48617 BC153182 AAI53183 BM674109 BM715757 BQ636049 EL945964 M33478 AAA35486 XM_011509603 XP_011507905 NM_002597 NP_002588 NM_022576 NP_072098 NM_022577
Function May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX. {ECO:0000269|PubMed:10866677}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:10866677}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:10866677}. Photoreceptor inner segment {ECO:0000269|PubMed:10866677}. Nucleus {ECO:0000269|PubMed:10866677}. Note=Outer and inner segments of the rod cells.
Top Pathways Olfactory transduction

Phd (E-1) - sc-398752 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Phd (E-1): sc-398752. Western blot analysis of Phd expression in rat eye (A) and mouse eye (B) tissue extracts.

Phd (G-7) - sc-271769 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Phd (G-7): sc-271769. Western blot analysis of Phd expression in non-transfected: sc-117752 (A) and mouse Phd transfected: sc-122529 (B) 293T whole cell lysates.

Phd (C-20) - sc-18415 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Phd (H-110) - sc-28850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Phd (H-110): sc-28850. Western blot analysis of Phd expression in non-transfected: sc-117752 (A) and mouse Phd transfected: sc-122529 (B) 293T whole cell lysates and rat eye tissue extract (C).

Phd (N-15) - sc-18413 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Phd (N-15): sc-18413. Western blot analysis of phosducin expression in rat eye extract.

p-Phd (Ser 73) - sc-23774 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PHOS antibody - ab170651 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PHOS antibody (ab170651) at 1/100 dilution + CEM cell line lysate at 35 µgdeveloped using the ECL technique

Anti-PDC Antibody (aa59-88, AP) - LS-C238867 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa59-88, APC) - LS-C238868 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa59-88, Biotin) - LS-C238869 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa59-88, FITC) - LS-C238870 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa59-88, PE) - LS-C238871 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa59-88, Azide-free, HRP) - LS-C248439 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa58-89) - LS-C323873 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PDC Antibody (aa59-88) - LS-C163458 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PDC Antibody western blot of CEM cell line lysates (35 ug/lane). The PDC antibody detected the PDC protein (arrow).

Phosducin Antibody - NBP1-87773 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Phosducin Antibody [NBP1-87773] - Staining of human cell line U-251MG shows positivity in cytoplasm.

Phosducin Antibody - H00005132-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PDC antibody produced in mouse - SAB1412733 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
<B>Immunoblotting</B><BR/>Anti-PDC:<B>Cat. No. SAB1412733</B>: Antibody concentration: 0.1–5 μg/mL. Immunofluorescence band of ~21.3 kDa using PDC transfected 293T lysate.<BR/><B>Lane</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PDC antibody produced in rabbit - HPA028432 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PDC: <B>Cat. No. HPA028432</B>: Immunohistochemical staining of human small intestine shows strong membranous positivity in glandular cells.

ANTI-PDC (CENTER) antibody produced in rabbit - SAB1304924 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PDC (Center): <B>Cat. No. SAB1304924</B>: PDC Antibody (Center) western blot analysis in CEM cell line lysates (35 μg/lane).

PDC-Antibody-Center - AP12439c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PDC Antibody (Center) (Cat. #AP12439c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PDC antibody detected the PDC protein (arrow).

PDC Antibody - middle region (OAAB08706) - OAAB08706 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Phosducin / PDC (Center) antibody - AP53227PU-N from Acris Antibodies

Prices $330.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of Phosducin / PDC Antibody (Center) Cat.-No AP53227PU-N in CEM cell line lysates (35ug/lane). This demonstrates the PDC antibody detected the PDC protein (arrow).

Phosducin / PDC antibody - H00005132-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PDC (full length) polyclonal antibody - DPABH-07577 from Creative Diagnostics

Host Mouse
Clonality Polyclonal
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