| Gene Symbol |
PDC
|
| Entrez Gene |
5132
|
| Alt Symbol |
MEKA, PHD, PhLOP, PhLP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phosducin
|
| Other Description |
33 kDa phototransducing protein|G beta gamma binding protein|phosducin-like orphan protein
|
| Swissprots |
Q9UP23 Q14816 P20941 Q9UP22
|
| Accessions |
AAA36210 EAW91212 EAW91213 EAW91214 EAW91215 P20941 AF076464 AAD43142 BC093839 AAH93839 BC112134 AAI12135 BC148616 AAI48617 BC153182 AAI53183 BM674109 BM715757 BQ636049 EL945964 M33478 AAA35486 XM_011509603 XP_011507905 NM_002597 NP_002588 NM_022576 NP_072098 NM_022577
|
| Function |
May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX. {ECO:0000269|PubMed:10866677}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:10866677}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:10866677}. Photoreceptor inner segment {ECO:0000269|PubMed:10866677}. Nucleus {ECO:0000269|PubMed:10866677}. Note=Outer and inner segments of the rod cells.
|
| Top Pathways |
Olfactory transduction
|
![Western Blot: Phosducin Overexpression Lysate (Adult Normal) [NBP2-06421] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Phosducin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4784_Phosducin%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06421-img0001.jpg)