Gene Symbol | PDC |
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Entrez Gene | 5132 |
Alt Symbol | MEKA, PHD, PhLOP, PhLP |
Species | Human |
Gene Type | protein-coding |
Description | phosducin |
Other Description | 33 kDa phototransducing protein|G beta gamma binding protein|phosducin-like orphan protein |
Swissprots | Q9UP23 Q14816 P20941 Q9UP22 |
Accessions | AAA36210 EAW91212 EAW91213 EAW91214 EAW91215 P20941 AF076464 AAD43142 BC093839 AAH93839 BC112134 AAI12135 BC148616 AAI48617 BC153182 AAI53183 BM674109 BM715757 BQ636049 EL945964 M33478 AAA35486 XM_011509603 XP_011507905 NM_002597 NP_002588 NM_022576 NP_072098 NM_022577 |
Function | May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. Inhibits the transcriptional activation activity of the cone-rod homeobox CRX. {ECO:0000269|PubMed:10866677}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:10866677}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:10866677}. Photoreceptor inner segment {ECO:0000269|PubMed:10866677}. Nucleus {ECO:0000269|PubMed:10866677}. Note=Outer and inner segments of the rod cells. |
Top Pathways | Olfactory transduction |
Phd CRISPR/Cas9 KO Plasmid (h) - sc-416502 from Santa Cruz Biotechnology
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Phd HDR Plasmid (h) - sc-416502-HDR from Santa Cruz Biotechnology
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Phd Double Nickase Plasmid (h) - sc-416502-NIC from Santa Cruz Biotechnology
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Phd Double Nickase Plasmid (h2) - sc-416502-NIC-2 from Santa Cruz Biotechnology
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Phd CRISPR Activation Plasmid (h) - sc-416502-ACT from Santa Cruz Biotechnology
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Phd CRISPR Activation Plasmid (h2) - sc-416502-ACT-2 from Santa Cruz Biotechnology
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Phd Lentiviral Activation Particles (h) - sc-416502-LAC from Santa Cruz Biotechnology
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Phd Lentiviral Activation Particles (h2) - sc-416502-LAC-2 from Santa Cruz Biotechnology
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Phd siRNA (h) - sc-40839 from Santa Cruz Biotechnology
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Phd shRNA Plasmid (h) - sc-40839-SH from Santa Cruz Biotechnology
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Phd shRNA (h) Lentiviral Particles - sc-40839-V from Santa Cruz Biotechnology
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Phosducin RNAi - H00005132-R02 from Novus Biologicals
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Phosducin RNAi - H00005132-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN2096 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2096 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03602 from Sigma-Aldrich
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PDC siRNA (Human) - CRH3413 from Cohesion Biosciences
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shRNA set against Human Pdc (NM_002597.4) - SHH372128 from Creative biogene
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PDC shRNA Plasmid (Human) - CHH3413 from Cohesion Biosciences
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