Gene Symbol | NAAA |
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Entrez Gene | 27163 |
Alt Symbol | ASAHL, PLT |
Species | Human |
Gene Type | protein-coding |
Description | N-acylethanolamine acid amidase |
Other Description | ASAH-like protein|N-acylethanolamine-hydrolyzing acid amidase|acid ceramidase-like protein |
Swissprots | Q96EY2 Q02083 Q5KTF2 Q9BRA8 |
Accessions | EAX05756 EAX05757 EAX05758 EAX05759 EAX05760 Q02083 AB161353 BAD88528 AK024677 AK301132 BAG62724 AK309271 AV723847 BC006388 AAH06388 BC011854 BM682921 BM763257 DR156596 M92449 AAA60119 W47597 XM_005262920 XP_005262977 XM_005262921 XP_005262978 XM_005262923 XP_005262980 XM_005262924 XP_005262981 XM_005262925 XP_005262982 XM_006714180 XP_006714243 XM_011531852 XP_011530154 XM_011531853 XP_011530155 XM_011531854 XP_011530156 NM_001042402 NP_001035861 NM_014435 NP_055250 |
Function | Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N- palmitoylethanolamine > N-myristoylethanolamine > N- lauroylethanolamine = N-stearoylethanolamine > N- arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N- lauroylsphingosine and N-palmitoylsphingosine. {ECO:0000269|PubMed:15655246}. |
Subcellular Location | Lysosome {ECO:0000305|PubMed:10610717, ECO:0000305|PubMed:15655246}. |
Tissue Specificity | Expressed in numerous tissues, with highest levels in liver and kidney, followed by pancreas. {ECO:0000269|PubMed:10610717}. |
Human ASAHL full length protein - ab162104 from Abcam
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Human ASAHL protein fragment - ab162105 from Abcam
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NAAA / ASAHL Antibody Blocking Peptide - LS-E5979 from LifeSpan Bioscience
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NAAA / ASAHL Antibody Blocking Peptide - LS-E16498 from LifeSpan Bioscience
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Recombinant Human ASAHL/N-acylethanolamine-hydrolyzing Acid Amidase Protein - H00027163-P01 from Novus Biologicals
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Recombinant Human ASAHL/N-acylethanolamine-hydrolyzing Acid Amidase Protein - H00027163-Q01 from Novus Biologicals
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ASAH2/N-acylsphingosine Amidohydrolase-2 Blocking Peptide - NBP1-76360PEP from Novus Biologicals
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NAAA-Antibody-C-term-Blocking-Peptide - BP18542b from Abgent, a WuXi AppTec company
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Recombinant Human ASAHL, CF - 4494-AH-010 from R&D Systems
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ASAHL Blocking Peptide - 33R-9833 from Fitzgerald
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Human NAAA Protein - abx068204 from Abbexa
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NAAA / ASAHL - H00027163-P01-10 from Acris Antibodies
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NAAA / ASAHL - H00027163-P01-25 from Acris Antibodies
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NAAA / ASAHL - H00027163-Q01-10 from Acris Antibodies
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NAAA / ASAHL - H00027163-Q01-25 from Acris Antibodies
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N-Acylethanolamine Acid Amidase (NAAA), Human - 20-8967 from ARP American Research Products
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NAAA fusion protein - Ag9861 from Proteintech Group
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NAAA fusion protein - Ag9817 from Proteintech Group
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Recombinant Human NAAA, His-tagged - NAAA-34H from Creative Biomart
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Recombinant Human NAAA, GST-tagged - NAAA-1165H from Creative Biomart
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Recombinant N-Acylethanolamine Acid Amidase (NAAA) - RPE690Hu01 from Uscn Life Science Inc.
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Recombinant N-Acylethanolamine Acid Amidase (NAAA) - RPE690Hu01 from Cloud-clone
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Recombinant Human ASAHL Protein, CF - 4494-AH from R&D Systems
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N-Acylethanolamine Acid Amidase (NAAA) - RPU142930 from Biomatik
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ASAHL, Recombinant Protein - MBS638135 from MyBioSource
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