SHH

Gene Symbol SHH
Entrez Gene 6469
Alt Symbol HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS
Species Human
Gene Type protein-coding
Description sonic hedgehog
Other Description sonic hedgehog homolog|sonic hedgehog protein
Swissprots A4D247 Q15465 Q75MC9
Accessions AAB67604 AAQ87879 AAS01990 ADL14518 BAA34689 EAL23913 EAX04543 Q15465 AY927450 AY927451 AY927452 AY927453 AY927455 BC111925 AAI11926 L38518 AAA62179 XM_011516479 XP_011514781 XM_011516480 XP_011514782 XM_011516481 XP_011514783 XM_011516482 XP_011514784 NM_000193 NP_000184
Function Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior- posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). {ECO:0000250}.
Subcellular Location Sonic hedgehog protein C-product: Secreted, extracellular space {ECO:0000250}. Note=The C-terminal peptide diffuses from the cell. {ECO:0000250}.
Tissue Specificity Expressed in fetal intestine, liver, lung, and kidney. Not expressed in adult tissues.
Top Pathways Hedgehog signaling pathway, Basal cell carcinoma

Human SHH cDNA clone(NM_000193.2) - CDFH017514 from Creative Biomart

Species Human
Accession NM_000193.2

Human SHH ORF Clone(NM_000193.2) - CDCR279152 from Creative Biomart

Species Human
Accession NM_000193.2

Human SHH ORF Clone(NM_000193.2) - CDCR279153 from Creative Biomart

Species Human
Accession NM_000193.2

Human SHH ORF Clone(NM_000193.2) - CDCR279154 from Creative Biomart

Species Human
Accession NM_000193.2

Human SHH ORF Clone(NM_000193.2) - CDCL175427 from Creative Biomart

Species Human
Accession NM_000193.2

human SHH ORF clone - CDCH079988 from Creative Biomart

Species Human
Accession NM_000193

human SHH ORF clone - CDCH079989 from Creative Biomart

Human Sonic Hedgehog ORF clone(NM_000193.2) - CDCL186264 from Creative biogene

Species Human

Human HHG1 Gene - orb90959 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human

Human SHH cDNA Clone(NM_000193.2) - CDFH017514 from Creative biogene

Species Human
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