Gene Symbol | SART1 |
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Entrez Gene | 9092 |
Alt Symbol | Ara1, HOMS1, SART1259, SNRNP110, Snu66 |
Species | Human |
Gene Type | protein-coding |
Description | squamous cell carcinoma antigen recognized by T cells |
Other Description | IgE autoantigen|SART-1|SART1(259) protein|SART1(800) protein|SNU66 homolog|U4/U6.U5 tri-snRNP-associated 110 kDa protein|U4/U6.U5 tri-snRNP-associated protein 1|hSART-1|hSnu66|small nuclear ribonucleoprotein 110kDa (U4/U6.U5)|squamous cell carcinoma antigen recognised by T cells|squamous cell carcinoma antigen recognized by T cells 1|squamous cell carcinoma antigen recognized by T-cells 1 |
Swissprots | O43290 Q53GB5 A6NDN1 |
Accessions | AAD20223 EAW74474 EAW74475 O43290 AB006198 BAA24056 AF353625 AAK49523 AK223016 BAD96736 AK293200 BAG56740 AK297589 BAG59976 AK298184 BAG60455 AK309104 AU136920 AW082868 BC001058 AAH01058 BC018607 BM668558 BM693243 BT006637 AAP35283 BX648500 DQ891694 ABM82620 EU176645 ABW03446 Y14314 CAA74694 XM_011545344 XP_011543646 XM_011545345 XP_011543647 XR_950099 NM_005146 NP_005137 |
Function | Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. {ECO:0000269|PubMed:11350945}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11350945, ECO:0000269|PubMed:9449708}. Note=Found in the nucleus of mitogen- activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:9449708}. |
Top Pathways | Spliceosome |
Human SART1 full length protein - ab160334 from Abcam
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Human SART1 peptide - ab45491 from Abcam
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Human SART1 protein fragment - ab160335 from Abcam
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SART1 Antibody Blocking Peptide - LS-E25466 from LifeSpan Bioscience
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Recombinant Human SART1 Protein - H00009092-P01 from Novus Biologicals
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Recombinant Human SART1 Protein - H00009092-Q01 from Novus Biologicals
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SART1 blocking peptide - GTX89682-PEP from GeneTex
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SART1 Peptide - AC21-0295-P from Abcore
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SART1 - H00009092-P01 from Acris Antibodies
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SART1 - H00009092-Q01-10 from Acris Antibodies
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SART1 - H00009092-Q01-25 from Acris Antibodies
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SART1 Peptide - 46-337P from ProSci
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SART1 fusion protein - ag18478 from Proteintech Group
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Recombinant Human U4/U6.U5 tri-snRNP-associated protein 1(SART1) - CSB-YP020711HU CSB-EP020711HU CSB-BP020711HU CSB-MP020711HU from Cusabio
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SART1, Peptide - MBS426863 from MyBioSource
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SART1 Recombinant Protein Antigen - NBP1-89024PEP from Novus Biologicals
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SART1 Recombinant Protein Antigen - NBP1-89023PEP from Novus Biologicals
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SART1 Protein - NBP1-89022PEP from Novus Biologicals
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SART1 Peptide, Human - M34GP13791H from Creative Peptides
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SART1 Immunizing peptide - orb16433 from Biorbyt
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