SART1

Gene Symbol SART1
Entrez Gene 9092
Alt Symbol Ara1, HOMS1, SART1259, SNRNP110, Snu66
Species Human
Gene Type protein-coding
Description squamous cell carcinoma antigen recognized by T cells
Other Description IgE autoantigen|SART-1|SART1(259) protein|SART1(800) protein|SNU66 homolog|U4/U6.U5 tri-snRNP-associated 110 kDa protein|U4/U6.U5 tri-snRNP-associated protein 1|hSART-1|hSnu66|small nuclear ribonucleoprotein 110kDa (U4/U6.U5)|squamous cell carcinoma antigen recognised by T cells|squamous cell carcinoma antigen recognized by T cells 1|squamous cell carcinoma antigen recognized by T-cells 1
Swissprots O43290 Q53GB5 A6NDN1
Accessions AAD20223 EAW74474 EAW74475 O43290 AB006198 BAA24056 AF353625 AAK49523 AK223016 BAD96736 AK293200 BAG56740 AK297589 BAG59976 AK298184 BAG60455 AK309104 AU136920 AW082868 BC001058 AAH01058 BC018607 BM668558 BM693243 BT006637 AAP35283 BX648500 DQ891694 ABM82620 EU176645 ABW03446 Y14314 CAA74694 XM_011545344 XP_011543646 XM_011545345 XP_011543647 XR_950099 NM_005146 NP_005137
Function Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA. {ECO:0000269|PubMed:11350945}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11350945, ECO:0000269|PubMed:9449708}. Note=Found in the nucleus of mitogen- activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:9449708}.
Top Pathways Spliceosome

SART-1 (E-2) - sc-376307 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SART-1 (E-2): sc-376307. Western blot analysis of SART-1 expression in Jurkat whole cell lysate.

SART-1 (C-20) - sc-55981 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SART-1 (A-5) - sc-376460 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SART-1 (A-5): sc-376460. Western blot analysis of SART-1 expression in Jurkat nuclear extract (A) and HeLa whole cell lysate (B).

SART-1 (F-4) - sc-376288 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SART-1 (F-4): sc-376288. Western blot analysis of SART-1 expression in Jurkat nuclear extract.

SART-1 (H-300) - sc-292462 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SART-1 (H-300): sc-292462. Western blot analysis of SART-1 expression in Jurkat (A), HeLa (B), NCI-H1299 (C), MOLT-4 (D) and Raji (E) whole cell lysates.

SART-1 (N-16) - sc-55984 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SART-1 (N-16): sc-55984. Western blot analysis of SART-1 expression in Jurkat nuclear extract.

Anti-SART1 antibody - ab95957 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SART1 antibody (ab95957) at 1/5000 dilution + A431 whole cell lysate at 30 µg

Anti-SART1 antibody - ab88583 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-SART1 antibody (ab88583) at 1 µg/ml + Jurkat cell lysate at 50 µgSecondaryGoat anti-Mouse IgG (H+L) HRP at 1/50000 dilution

Anti-SART1 antibody - ab22820 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-SART1 antibody (ab22820) at 0.03 µg/ml + Hela lysate (35µg protein in RIPA buffer)

Anti-SART1 antibody - ab96654 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SART1 antibody (ab96654) at 1/5000 dilutionLane 1 : H1299 whole cell lysateLane 2 : HeLa whole cell lysateLane 3 : Molt-4 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-SART1 antibody [EPR14563(B)] - ab181867 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14563(B)
All lanes : Anti-SART1 antibody [EPR14563(B)] (ab181867) at 1/50000 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysateLane 3 : MOLT4 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-SART1 Antibody (aa675-725) - LS-C288215 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SART1 Antibody (aa750-800) - LS-C288217 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SART1 Antibody (aa2-14) - LS-C55435 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.03 ug/ml) staining of Hela lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SART1 Antibody (aa533-792) - LS-C186192 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate). A: H1299, B: Hela, C: Molt-4 . 7.5% SDS PAGE. SART1 antibody diluted at 1:5000.

Anti-SART1 Antibody - LS-C181999 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SART1 Antibody - SART1 antibody was tested in mouse testes using DAB with hematoxylin counterstain.

Anti-SART1 Antibody (aa137-447) - LS-C185540 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Cal27 xenograft using SART1 antibody at 1:500 dilution.

SART1 Antibody - NBP2-14836 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SART1 Antibody [NBP2-14836] - SART1 antibody tested in NIH-3T3 cell lysate.

SART1 Antibody (865709) - MAB8034 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 865709
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line and EL‑4 mouse lymphoblast cell line. Gels were loaded with 20 µg of HepG2 and 30 µg of EL-4 cytoplasmic (Cyto) extracts and 10 µg of HepG2 and 15 µg of EL-4 nuclear (Nuc) extracts. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human SART1 Monoclonal Antibody (Catalog # MAB8034) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for SART1 at approximately 120 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

SART1 Antibody - NBP1-89024 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SART1 Antibody [NBP1-89024] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).

SART1 Antibody - NBP1-89023 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SART1 Antibody [NBP1-89023] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG.

SART1 Antibody - NBP1-89022 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SART1 Antibody [NBP1-89022] - Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.

SART1 Antibody - H00009092-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: SART1 Antibody [H00009092-B01P] - Analysis of SART1 expression in Jurkat.

SART1 Antibody - NB100-68233 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SART1 Antibody - NB100-1145 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: SART1 Antibody [NB100-1145] - NB100-1145 (0.03ug/ml) staining of Hela lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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