Gene Symbol | CCL3 |
---|---|
Entrez Gene | 6348 |
Alt Symbol | G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 3 |
Other Description | C-C motif chemokine 3|G0/G1 switch regulatory protein 19-1|PAT 464.1|SIS-beta|macrophage inflammatory protein 1-alpha|small inducible cytokine A3 (homologous to mouse Mip-1a)|tonsillar lymphocyte LD78 alpha protein |
Swissprots | P10147 |
Accessions | AAA35858 AAB47170 ABK41952 BAA14172 CAA27643 EAW80100 P10147 AF043339 AAC03539 BC071834 AAH71834 BC171831 AAI71831 BC171891 AAI71891 BX103455 D00044 BAA00029 D63785 BAA09855 M23452 AAA36316 M25315 AAA57255 X03754 CAA27388 NM_002983 NP_002974 |
Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). {ECO:0000269|PubMed:8525373}. |
Subcellular Location | Secreted. |
Top Pathways | Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway, Chemokine signaling pathway, Chagas disease (American trypanosomiasis), Rheumatoid arthritis |
MIP-1α (E-2) - sc-393899 from Santa Cruz Biotechnology
|
||||||||||
MIP-1α (C-16) - sc-1381 from Santa Cruz Biotechnology
|
||||||||||
MIP-1α (D-3) - sc-166942 from Santa Cruz Biotechnology
|
||||||||||
MIP-1α (FL-92) - sc-33203 from Santa Cruz Biotechnology
|
||||||||||
MIP-1α (N-20) - sc-1382 from Santa Cruz Biotechnology
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody - ab9673 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody - ab32609 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody - ab9859 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody - ab7631 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody - ab166829 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody [199] - ab18690 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody (Biotin) - ab84441 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody [EP493Y] - ab46786 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody [M6110647] - ab47860 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody [MM0154-11F16] - ab89546 from Abcam
|
||||||||||
Anti-Macrophage Inflammatory Protein 1 alpha / CCL3 antibody, prediluted - ab32610 from Abcam
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody (aa29-92) IHC-plus™ - LS-B11609 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C8603 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C8607 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C25322 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C25321 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C25323 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C25324 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C25325 from LifeSpan Bioscience
|
||||||||||
Anti-CCL3 / MIP-1-Alpha Antibody - LS-C25328 from LifeSpan Bioscience
|