Gene Symbol | MTBP |
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Entrez Gene | 27085 |
Alt Symbol | MDM2BP |
Species | Human |
Gene Type | protein-coding |
Description | MDM2 binding protein |
Other Description | MDM2 (mouse double minute 2)-binding protein, 104kD|Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa|mdm2-binding protein |
Swissprots | Q96DY7 Q9HA89 B4DUR5 |
Accessions | EAW92006 EAW92007 Q96DY7 AK022122 BAB13965 AK300762 BAG62427 AL832671 BC013136 AAH13136 EU176294 ABW03745 EU176618 ABW03419 XM_011516962 XP_011515264 XM_011516963 XP_011515265 XR_928318 NM_022045 NP_071328 |
Function | Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. {ECO:0000250, ECO:0000269|PubMed:15632057}. |
MTBP (N-13) - sc-47174 from Santa Cruz Biotechnology
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MTBP (C-16) - sc-47171 from Santa Cruz Biotechnology
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MTBP (K-20) - sc-47173 from Santa Cruz Biotechnology
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MTBP (B-5) - sc-137201 from Santa Cruz Biotechnology
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MTBP (H-40) - sc-99047 from Santa Cruz Biotechnology
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Anti-MTBP antibody - ab115529 from Abcam
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Anti-MTBP antibody - ab198831 from Abcam
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Anti-MTBP antibody - ab8107 from Abcam
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Anti-MTBP antibody [PHL-1] - ab34704 from Abcam
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Anti-MTBP / Mdm2-Binding Protein Antibody (aa667-812) - LS-C19034 from LifeSpan Bioscience
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Anti-MTBP / Mdm2-Binding Protein Antibody (aa122-139) - LS-C53377 from LifeSpan Bioscience
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Anti-MTBP / Mdm2-Binding Protein Antibody (aa122-139) - LS-C83544 from LifeSpan Bioscience
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Anti-MTBP Antibody - LS-C26877 from LifeSpan Bioscience
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Anti-MTBP / Mdm2-Binding Protein Antibody (aa139-188) - LS-C201655 from LifeSpan Bioscience
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Anti-MTBP / Mdm2-Binding Protein Antibody IHC-plus⢠- LS-B10863 from LifeSpan Bioscience
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Anti-MTBP / Mdm2-Binding Protein Antibody (aa853-881) - LS-C98397 from LifeSpan Bioscience
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Anti-MTBP / Mdm2-Binding Protein Antibody (aa122-139) IHC-plus⢠- LS-B1378 from LifeSpan Bioscience
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MTBP Antibody - NBP1-86408 from Novus Biologicals
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MTBP Antibody - NBP1-76747 from Novus Biologicals
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MTBP Antibody - NBP2-19427 from Novus Biologicals
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MTBP Antibody - NBP2-19426 from Novus Biologicals
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MDM2BP Polyclonal Antibody - bs-6388R from Bioss
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Anti-MTBP, Intermediate Domain 2 antibody produced in rabbit - M3566 from Sigma-Aldrich
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Anti-MTBP antibody produced in rabbit - HPA025694 from Sigma-Aldrich
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Monoclonal Anti-MTBP antibody produced in mouse - SAB3701461 from Sigma-Aldrich
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