MTBP

Gene Symbol MTBP
Entrez Gene 27085
Alt Symbol MDM2BP
Species Human
Gene Type protein-coding
Description MDM2 binding protein
Other Description MDM2 (mouse double minute 2)-binding protein, 104kD|Mdm2, transformed 3T3 cell double minute 2, p53 binding protein binding protein, 104kDa|mdm2-binding protein
Swissprots Q96DY7 Q9HA89 B4DUR5
Accessions EAW92006 EAW92007 Q96DY7 AK022122 BAB13965 AK300762 BAG62427 AL832671 BC013136 AAH13136 EU176294 ABW03745 EU176618 ABW03419 XM_011516962 XP_011515264 XM_011516963 XP_011515265 XR_928318 NM_022045 NP_071328
Function Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. {ECO:0000250, ECO:0000269|PubMed:15632057}.

MTBP CRISPR/Cas9 KO Plasmid (h) - sc-404307 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP HDR Plasmid (h) - sc-404307-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP Double Nickase Plasmid (h) - sc-404307-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP Double Nickase Plasmid (h2) - sc-404307-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP CRISPR Activation Plasmid (h) - sc-404307-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP CRISPR Activation Plasmid (h2) - sc-404307-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP Lentiviral Activation Particles (h) - sc-404307-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP Lentiviral Activation Particles (h2) - sc-404307-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MTBP siRNA (h) - sc-61080 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTBP shRNA Plasmid (h) - sc-61080-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MTBP shRNA (h) Lentiviral Particles - sc-61080-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU036191 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14688 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14688 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02612 from Sigma-Aldrich

Category miRNA

MTBP siRNA (Human) - CRH8953 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MTBP (NM_022045.4) - SHH346144 from Creative biogene

Category siRNA
Species Reactivities Human

Human MTBP siRNA - orb269455 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MTBP shRNA Plasmid (Human) - CHH8953 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MTBP miRNA 3'UTR clone - MiUTR3H-08056 from Creative biogene

Species Reactivities Human
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