NELFE

Gene Symbol NELFE
Entrez Gene 7936
Alt Symbol D6S45, NELF-E, RD, RDBP, RDP
Species Human
Gene Type protein-coding
Description negative elongation factor complex member E
Other Description RD RNA binding protein|RD RNA-binding protein|RNA-binding protein RD|major histocompatibility complex gene RD|negative elongation factor E|negative elongation factor polypeptide E|nuclear protein
Swissprots Q96F56 Q5JP74 P18615 B4DUN1 A2BE08 B4DYX9 Q5JP75 Q9NPK2
Accessions AAA36308 AAB67979 AAK29466 CAB89308 EAX03551 EAX03552 EAX03553 P18615 AK300717 BAG62393 AK300898 BAH13370 AK302652 BAG63891 AK303152 BAG64255 BC025235 AAH25235 BC050617 AAH50617 BU935034 CD579634 DQ896847 ABM87846 JQ313904 AFH41798 L03411 AAC37523 X16105 CAA34231 XM_006715205 XP_006715268 XM_006725521 XP_006725584 XM_006725739 XP_006725802 XM_006725936 XP_006725999 XM_006726037 XP_006726100 XM_006726125 XP_006726188 XM_011514913 XP_011513215 XM_011547314 XP_011545616 XM_011547716 XP_011546018 XM_011548102 XP_011546404 XM_011548301 XP_011546603 XM_011548486 XP_011546788 NM_002904 NP_002895
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:11940650, ECO:0000269|PubMed:12612062}.
Subcellular Location Nucleus.
Tissue Specificity Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:12612062}.

NELF-E CRISPR/Cas9 KO Plasmid (h) - sc-401932 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E HDR Plasmid (h) - sc-401932-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E Double Nickase Plasmid (h) - sc-401932-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E Double Nickase Plasmid (h2) - sc-401932-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E CRISPR Activation Plasmid (h) - sc-401932-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E CRISPR Activation Plasmid (h2) - sc-401932-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E Lentiviral Activation Particles (h) - sc-401932-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E Lentiviral Activation Particles (h2) - sc-401932-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-E siRNA (h) - sc-38093 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-E shRNA Plasmid (h) - sc-38093-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-E shRNA (h) Lentiviral Particles - sc-38093-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-E RNAi - H00007936-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN18109 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18109 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00493 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00493

NELFE siRNA (Human) - CRH5321 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RDBP (NM_002904.5) - SHH391416 from Creative biogene

Category siRNA
Species Reactivities Human

Human NELFE siRNA - orb265823 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NELFE shRNA Plasmid (Human) - CHH5321 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RDBP miRNA 3'UTR clone - MiUTR1H-08717 from Creative biogene

Species Reactivities Human
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