Gene Symbol |
DDX25
|
Entrez Gene |
29118
|
Alt Symbol |
GRTH
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
DEAD (Asp-Glu-Ala-Asp) box helicase 25
|
Other Description |
ATP-dependent RNA helicase DDX25|DEAD (Asp-Glu-Ala-Asp) box polypeptide 25|DEAD box protein 25|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 25|gonadotropin-regulated testicular RNA helicase
|
Swissprots |
Q86W81 Q5XVN2 Q9UHL0 Q8IYP1 B2R6Z0
|
Accessions |
AAU84667 ABW87006 ABW87007 ACA64098 EAW67668 EAW67669 Q9UHL0 AF155140 AAF21371 AK295121 BAG58148 AK312772 BAG35637 BC031098 BC035388 AAH35388 BC050360 AAH50360 CD359894 CD657404 DC395868 XM_011542790 XP_011541092 XM_011542791 XP_011541093 NM_013264 NP_037396
|
Function |
ATP-dependent RNA helicase. Required for mRNA export and translation regulation during spermatid development (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:10608860}. Nucleus {ECO:0000250}. Note=Detected in both cytoplasm and nucleus of testicular cells. Also detected in chromatoid bodies of round spermatids (By similarity). {ECO:0000250}.
|
Tissue Specificity |
Highly expressed in the Leydig and germ cells of the testis and weakly expressed in the pituitary and hypothalamus. {ECO:0000269|PubMed:10608860, ECO:0000269|Ref.2}.
|